Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT03V27)

• DTP Name: Sodium bicarbonate cotransporter 3 (SLC4A7) DTP Info
• Gene Name: NBC3

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	3.96E-01	-1.37E-01	-3.55E-01
Adrenocortical carcinoma	2D11.Z	Kidney	7.60E-01	-2.55E-02	-1.45E-01
Alopecia	ED70	Skin from scalp	7.53E-01	7.67E-02	1.61E-01
Alzheimer's disease	8A20	Entorhinal cortex	5.63E-01	-3.75E-02	-1.40E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	4.00E-01	-3.12E-01	-5.45E-01
Aortic stenosis	BB70	Calcified aortic valve	7.82E-01	-3.55E-02	-9.31E-02
Apnea	7A40	Hyperplastic tonsil	1.53E-01	4.56E-01	9.01E-01
Arthropathy	FA00-FA5Z	Peripheral blood	4.13E-02	-2.91E-01	-6.45E-01
Asthma	CA23	Nasal and bronchial airway	7.68E-01	4.09E-02	8.45E-02
Atopic dermatitis	EA80	Skin	1.53E-13	4.45E-01	3.81E+00
Autism	6A02	Whole blood	8.53E-01	-4.28E-02	-1.30E-01
Autoimmune uveitis	9A96	Peripheral monocyte	3.89E-01	2.30E-01	1.08E+00
Autosomal dominant monocytopenia	4B04	Whole blood	8.89E-02	-2.31E-01	-7.35E-01
Bacterial infection of gingival	1C1H	Gingival tissue	7.91E-01	2.18E-02	5.12E-02
Batten disease	5C56.1	Whole blood	5.68E-01	1.66E-02	6.82E-02
Behcet's disease	4A62	Peripheral blood	8.31E-01	-1.73E-01	-5.56E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	8.69E-01	9.96E-02	3.37E-01
Bladder cancer	2C94	Bladder tissue	7.19E-01	-2.40E-01	-3.82E-01
Breast cancer	2C60-2C6Z	Breast tissue	6.43E-04	4.43E-02	7.11E-02
Cardioembolic stroke	8B11.20	Whole blood	2.53E-01	1.17E-01	3.75E-01
Cervical cancer	2C77	Cervical tissue	5.95E-01	3.43E-02	7.96E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	8.87E-01	8.24E-02	1.01E-01
Chronic hepatitis C	1E51.1	Whole blood	1.49E-02	-2.20E-01	-9.46E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	4.78E-01	4.10E-02	1.27E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	4.63E-02	-9.96E-02	-4.02E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.63E-01	1.41E-01	6.45E-01
Colon cancer	2B90	Colon tissue	6.86E-23	3.39E-01	9.85E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	4.57E-01	-3.08E-01	-6.32E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	7.50E-02	2.71E-01	6.62E-01
Endometriosis	GA10	Endometrium tissue	1.68E-02	-1.19E-01	-1.60E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	6.15E-01	-4.17E-02	-1.50E-01
Familial hypercholesterolemia	5C80.00	Whole blood	4.60E-04	-2.86E-01	-1.14E+00
Gastric cancer	2B72	Gastric tissue	1.32E-01	5.46E-01	1.64E+00
Glioblastopma	2A00.00	Nervous tissue	4.08E-133	7.56E-01	2.01E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	4.50E-03	4.34E-01	6.72E-01
Head and neck cancer	2D42	Head and neck tissue	9.01E-13	3.64E-01	1.17E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.37E-01	-7.40E-02	-5.81E-01
Huntington's disease	8A01.10	Whole blood	1.63E-01	-1.82E-01	-1.06E+00
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	6.01E-01	5.89E-02	8.32E-02
Immunodeficiency	4A00-4A20	Peripheral blood	8.11E-02	-9.75E-02	-5.68E-01
Influenza	1.00E+30	Whole blood	7.72E-04	-1.98E+00	-6.91E+00
Interstitial cystitis	GC00.3	Bladder tissue	4.26E-02	2.06E-01	7.44E-01
Intracranial aneurysm	8B01.0	Intracranial artery	5.91E-03	-5.10E-01	-1.20E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.11E-01	1.34E-01	3.66E-01
Ischemic stroke	8B11	Peripheral blood	9.77E-01	-4.45E-04	-1.25E-03
Juvenile idiopathic arthritis	FA24	Peripheral blood	5.09E-03	2.48E-01	4.04E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	1.27E-01	1.02E-01	4.43E-01
Lateral sclerosis	8B60.4	Skin	3.61E-01	-2.96E-01	-4.74E-01
Liver cancer	2C12.0	Liver tissue	1.10E-09	2.27E-01	1.18E+00
Liver failure	DB99.7-DB99.8	Liver tissue	1.33E-02	4.40E-01	1.55E+00
Lung cancer	2C25	Lung tissue	2.39E-16	2.88E-01	8.51E-01
Lupus erythematosus	4A40	Whole blood	5.52E-07	-6.39E-02	-2.69E-01
Major depressive disorder	6A70-6A7Z	Whole blood	8.44E-01	-4.20E-02	-6.83E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	8.26E-01	4.85E-02	1.69E-01
Melanoma	2C30	Skin	7.84E-01	-3.45E-01	-3.56E-01
Multiple myeloma	2A83.1	Bone marrow	2.51E-02	-2.62E-01	-1.15E+00
Multiple myeloma	2A83.1	Peripheral blood	2.54E-01	-2.18E-01	-3.83E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	3.92E-01	-1.23E-01	-2.96E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	9.43E-06	-2.20E-01	-8.06E-01
Myelofibrosis	2A20.2	Whole blood	3.33E-01	-8.54E-02	-4.63E-01
Myocardial infarction	BA41-BA50	Peripheral blood	5.07E-02	-3.82E-01	-5.19E-01
Myopathy	8C70.6	Muscle tissue	1.71E-01	1.25E-01	2.43E-01
Neonatal sepsis	KA60	Whole blood	3.79E-13	-4.40E-01	-7.81E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	3.75E-06	7.26E-01	2.68E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	1.59E-01	3.31E-02	6.00E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	7.11E-01	4.20E-01	5.04E-01
Olive pollen allergy	CA08.00	Peripheral blood	2.35E-01	-1.61E-01	-6.05E-01
Oral cancer	2B6E	Oral tissue	5.66E-03	2.26E-01	3.88E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	1.70E-01	2.23E-01	8.81E-01
Osteoporosis	FB83.1	Bone marrow	4.43E-01	1.78E-01	5.56E-01
Ovarian cancer	2C73	Ovarian tissue	4.23E-03	5.04E-01	1.46E+00
Pancreatic cancer	2C10	Pancreas	1.25E-01	1.90E-01	4.28E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	8.25E-01	-9.73E-02	-3.32E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	3.30E-05	-4.40E-01	-1.74E+00
Pituitary cancer	2D12	Pituitary tissue	4.47E-01	-9.79E-02	-1.92E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.75E-01	-1.09E-01	-2.13E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.69E-02	-1.70E-01	-8.16E-01
Polycythemia vera	2A20.4	Whole blood	1.57E-10	-2.35E-01	-1.33E+00
Pompe disease	5C51.3	Biceps muscle	4.80E-01	-1.22E-01	-2.80E-01
Preterm birth	KA21.4Z	Myometrium	7.33E-01	-5.60E-02	-3.46E-01
Prostate cancer	2C82	Prostate	1.56E-05	4.58E-01	1.11E+00
Psoriasis	EA90	Skin	8.68E-03	1.38E-01	3.43E-01
Rectal cancer	2B92	Rectal colon tissue	3.91E-07	5.01E-01	3.87E+00
Renal cancer	2C90-2C91	Kidney	8.50E-02	2.11E-01	3.78E-01
Retinoblastoma	2D02.2	Uvea	1.11E-12	-3.88E+00	-6.10E+00
Rheumatoid arthritis	FA20	Synovial tissue	2.23E-07	5.99E-01	2.78E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	8.57E-01	2.41E-02	1.32E-01
Schizophrenia	6A20	Prefrontal cortex	3.63E-01	1.30E-01	2.43E-01
Schizophrenia	6A20	Superior temporal cortex	3.06E-01	-5.24E-03	-7.16E-02
Scleroderma	4A42.Z	Whole blood	8.67E-01	-5.84E-02	-3.30E-01
Seizure	8A60-8A6Z	Whole blood	1.28E-01	2.88E-01	7.60E-01
Sensitive skin	EK0Z	Skin	5.56E-01	6.88E-02	4.92E-01
Sepsis with septic shock	1G41	Whole blood	6.26E-32	-5.48E-01	-9.38E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	6.35E-01	-1.25E-01	-1.98E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	8.11E-03	-2.63E-01	-6.14E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	7.89E-01	2.79E-05	1.69E-04
Sjogren's syndrome	4A43.2	Salivary gland tissue	6.43E-01	4.31E-02	2.19E-01
Skin cancer	2C30-2C3Z	Skin	9.12E-36	7.09E-01	1.40E+00
Thrombocythemia	3B63	Whole blood	2.10E-03	-1.54E-01	-8.72E-01
Thrombocytopenia	3B64	Whole blood	5.82E-01	-1.23E-01	-1.83E-01
Thyroid cancer	2D10	Thyroid	3.46E-12	2.59E-01	7.56E-01
Tibial muscular dystrophy	8C75	Muscle tissue	7.69E-01	3.61E-02	6.81E-02
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	9.20E-01	1.68E-02	7.69E-02
Type 2 diabetes	5A11	Liver tissue	1.15E-01	5.94E-02	6.85E-01
Ureter cancer	2C92	Urothelium	7.37E-01	-3.07E-02	-1.85E-01
Uterine cancer	2C78	Endometrium tissue	6.43E-01	1.84E-01	2.77E-01
Vitiligo	ED63.0	Skin	6.22E-03	3.97E-01	1.31E+00