Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT3BA8L)

• DTP Name: Sodium-dependent dopamine transporter (SLC6A3) DTP Info
• Gene Name: DAT1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.40E-05	1.43E-01	5.91E-01
Adrenocortical carcinoma	2D11.Z	Kidney	6.58E-01	-5.96E-02	-2.70E-01
Alopecia	ED70	Skin from scalp	9.61E-01	-3.63E-02	-1.71E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.11E-01	1.59E-02	5.57E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	7.44E-01	-5.93E-02	-5.60E-01
Aortic stenosis	BB70	Calcified aortic valve	1.28E-01	1.62E-01	4.08E-01
Apnea	7A40	Hyperplastic tonsil	2.06E-01	-1.10E-01	-1.20E+00
Arthropathy	FA00-FA5Z	Peripheral blood	4.52E-01	4.92E-02	3.14E-01
Asthma	CA23	Nasal and bronchial airway	8.82E-01	8.73E-02	2.07E-01
Atopic dermatitis	EA80	Skin	8.95E-01	1.91E-03	1.31E-02
Autism	6A02	Whole blood	7.76E-01	-1.66E-02	-7.74E-02
Autoimmune uveitis	9A96	Peripheral monocyte	2.02E-01	-8.98E-02	-7.56E-01
Autosomal dominant monocytopenia	4B04	Whole blood	8.06E-01	-4.08E-02	-2.74E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.71E-04	1.09E-01	4.76E-01
Batten disease	5C56.1	Whole blood	1.77E-01	8.43E-02	6.92E-01
Behcet's disease	4A62	Peripheral blood	6.83E-01	-7.24E-03	-4.07E-02
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	6.12E-01	4.71E-03	2.90E-02
Bladder cancer	2C94	Bladder tissue	7.12E-01	2.26E-02	1.53E-01
Breast cancer	2C60-2C6Z	Breast tissue	2.37E-01	3.26E-02	1.51E-01
Cardioembolic stroke	8B11.20	Whole blood	3.13E-03	2.02E-01	1.34E+00
Cervical cancer	2C77	Cervical tissue	2.52E-03	-1.02E-01	-7.15E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	2.18E-01	-6.97E-03	-1.95E-02
Chronic hepatitis C	1E51.1	Whole blood	8.84E-03	2.16E-01	1.54E+00
Chronic obstructive pulmonary disease	CA22	Lung tissue	7.63E-01	-2.77E-02	-1.47E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	1.34E-01	9.53E-02	4.05E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	3.17E-01	-6.18E-02	-3.36E-01
Colon cancer	2B90	Colon tissue	1.57E-01	4.61E-02	1.91E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	4.08E-01	9.30E-02	3.90E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	3.11E-01	-2.04E-01	-7.15E-01
Endometriosis	GA10	Endometrium tissue	6.60E-01	3.06E-02	1.54E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.75E-01	-5.65E-03	-4.37E-02
Familial hypercholesterolemia	5C80.00	Whole blood	4.80E-01	1.71E-02	8.10E-02
Gastric cancer	2B72	Gastric tissue	1.75E-01	1.40E-01	7.95E-01
Glioblastopma	2A00.00	Nervous tissue	7.92E-06	8.67E-02	9.70E-02
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.10E-01	-1.30E-01	-3.97E-01
Head and neck cancer	2D42	Head and neck tissue	3.03E-02	6.51E-02	3.50E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.26E-01	-9.36E-02	-6.43E-01
Huntington's disease	8A01.10	Whole blood	8.93E-01	0.00E+00	0.00E+00
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	9.27E-01	1.98E-02	1.70E-01
Immunodeficiency	4A00-4A20	Peripheral blood	6.42E-01	5.19E-03	4.01E-02
Influenza	1.00E+30	Whole blood	5.06E-02	4.18E-01	2.65E+00
Interstitial cystitis	GC00.3	Bladder tissue	3.75E-01	4.20E-02	4.88E-01
Intracranial aneurysm	8B01.0	Intracranial artery	2.28E-03	2.12E-01	8.87E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	3.92E-01	-4.41E-02	-1.50E-01
Ischemic stroke	8B11	Peripheral blood	1.73E-01	5.61E-02	4.07E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	8.70E-02	1.39E-02	5.02E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	4.01E-01	2.11E-01	1.01E+00
Lateral sclerosis	8B60.4	Skin	3.74E-01	1.01E-01	6.99E-01
Liver cancer	2C12.0	Liver tissue	2.73E-02	-1.25E-01	-5.77E-01
Liver failure	DB99.7-DB99.8	Liver tissue	6.92E-01	1.04E-03	4.37E-03
Lung cancer	2C25	Lung tissue	2.47E-47	2.43E-01	1.10E+00
Lupus erythematosus	4A40	Whole blood	1.43E-01	-1.40E-01	-2.14E-01
Major depressive disorder	6A70-6A7Z	Whole blood	8.42E-01	3.31E-02	1.42E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	4.17E-01	4.04E-03	2.45E-02
Melanoma	2C30	Skin	4.18E-02	4.16E-01	7.63E-01
Multiple myeloma	2A83.1	Bone marrow	1.25E-04	4.19E-01	2.56E+00
Multiple myeloma	2A83.1	Peripheral blood	4.71E-01	1.06E-02	5.88E-02
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	4.97E-01	-7.58E-02	-2.51E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	4.67E-01	-6.54E-02	-3.60E-01
Myelofibrosis	2A20.2	Whole blood	1.63E-01	-5.36E-02	-4.56E-01
Myocardial infarction	BA41-BA50	Peripheral blood	9.66E-02	3.27E-01	6.31E-01
Myopathy	8C70.6	Muscle tissue	1.13E-01	-6.96E-02	-4.77E-01
Neonatal sepsis	KA60	Whole blood	2.92E-01	3.64E-02	1.48E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.61E-05	2.96E-01	6.76E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	6.20E-01	5.38E-02	2.46E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	7.63E-01	-1.21E-01	-5.94E-01
Olive pollen allergy	CA08.00	Peripheral blood	9.45E-01	-1.94E-01	-4.45E-01
Oral cancer	2B6E	Oral tissue	6.65E-01	-5.55E-03	-2.04E-02
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.31E-01	-8.97E-02	-4.32E-01
Osteoporosis	FB83.1	Bone marrow	2.42E-02	6.22E-01	4.57E+00
Ovarian cancer	2C73	Ovarian tissue	2.41E-02	-1.99E-01	-6.56E-01
Pancreatic cancer	2C10	Pancreas	8.23E-03	-3.27E-01	-8.79E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	1.08E-03	-3.08E+00	-1.99E+00
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	7.45E-01	-3.79E-03	-3.55E-02
Pituitary cancer	2D12	Pituitary tissue	2.09E-01	1.43E-01	4.31E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	8.11E-01	-5.84E-02	-1.77E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	7.38E-01	-4.04E-03	-2.37E-02
Polycythemia vera	2A20.4	Whole blood	5.13E-02	-5.21E-02	-4.12E-01
Pompe disease	5C51.3	Biceps muscle	8.40E-01	8.55E-02	4.81E-01
Preterm birth	KA21.4Z	Myometrium	7.34E-01	-3.24E-02	-2.30E-01
Prostate cancer	2C82	Prostate	4.56E-03	-6.57E-01	-1.02E+00
Psoriasis	EA90	Skin	6.58E-11	-2.68E-01	-5.92E-01
Rectal cancer	2B92	Rectal colon tissue	1.04E-01	-1.44E-01	-8.57E-01
Renal cancer	2C90-2C91	Kidney	9.53E-16	1.10E+00	3.12E+00
Retinoblastoma	2D02.2	Uvea	6.57E-02	1.10E-01	8.03E-01
Rheumatoid arthritis	FA20	Synovial tissue	6.45E-01	4.65E-02	1.08E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.44E-01	7.16E-03	4.81E-02
Schizophrenia	6A20	Prefrontal cortex	7.05E-01	-7.30E-03	-4.08E-02
Schizophrenia	6A20	Superior temporal cortex	5.94E-01	-3.30E-02	-1.96E-01
Scleroderma	4A42.Z	Whole blood	6.64E-02	1.33E-01	7.46E-01
Seizure	8A60-8A6Z	Whole blood	7.73E-01	3.41E-03	1.34E-02
Sensitive skin	EK0Z	Skin	4.44E-01	4.57E-03	2.59E-02
Sepsis with septic shock	1G41	Whole blood	1.60E-04	9.13E-02	4.00E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	4.35E-01	2.03E-02	1.81E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	5.24E-01	-1.65E-02	-5.46E-02
Simpson golabi behmel syndrome	LD2C	Adipose tissue	3.13E-01	7.42E-02	8.98E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	3.88E-02	-4.17E-01	-2.13E+00
Skin cancer	2C30-2C3Z	Skin	2.82E-03	-2.65E-01	-4.31E-01
Thrombocythemia	3B63	Whole blood	2.57E-01	-1.01E-01	-8.06E-01
Thrombocytopenia	3B64	Whole blood	8.02E-01	-4.42E-03	-1.17E-02
Thyroid cancer	2D10	Thyroid	1.32E-04	-2.29E-01	-7.43E-01
Tibial muscular dystrophy	8C75	Muscle tissue	4.88E-02	-1.69E-01	-1.14E+00
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	2.31E-01	2.20E-01	1.42E+00
Type 2 diabetes	5A11	Liver tissue	2.72E-01	-1.52E-01	-6.81E-01
Ureter cancer	2C92	Urothelium	5.95E-01	-5.05E-02	-2.80E-01
Uterine cancer	2C78	Endometrium tissue	1.54E-07	-1.41E-01	-5.14E-01
Vitiligo	ED63.0	Skin	3.63E-01	8.85E-02	7.49E-01