Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT8ACN1)

• DTP Name: Sodium/myo-inositol cotransporter (SLC5A3) DTP Info
• Gene Name: SMIT

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	4.58E-01	-2.78E-01	-2.92E-01
Adrenocortical carcinoma	2D11.Z	Kidney	2.74E-01	1.25E-01	2.04E-01
Alopecia	ED70	Skin from scalp	3.55E-01	-3.48E-02	-1.27E-01
Alzheimer's disease	8A20	Entorhinal cortex	6.58E-06	4.68E-01	9.02E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	9.64E-02	-6.13E-01	-9.04E-01
Aortic stenosis	BB70	Calcified aortic valve	4.70E-01	-4.45E-01	-3.77E-01
Apnea	7A40	Hyperplastic tonsil	7.79E-02	9.47E-01	1.48E+00
Arthropathy	FA00-FA5Z	Peripheral blood	2.36E-01	-4.04E-02	-1.16E-01
Asthma	CA23	Nasal and bronchial airway	1.57E-04	2.01E-01	2.63E-01
Atopic dermatitis	EA80	Skin	4.68E-01	1.63E-01	3.26E-01
Autism	6A02	Whole blood	6.23E-02	1.71E-01	3.85E-01
Autoimmune uveitis	9A96	Peripheral monocyte	1.30E-02	2.09E+00	1.01E+01
Autosomal dominant monocytopenia	4B04	Whole blood	6.91E-01	3.43E-02	5.97E-02
Bacterial infection of gingival	1C1H	Gingival tissue	1.86E-01	4.45E-02	1.03E-01
Batten disease	5C56.1	Whole blood	5.37E-01	3.75E-02	1.68E-01
Behcet's disease	4A62	Peripheral blood	8.37E-01	-8.70E-02	-2.01E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	1.05E-01	4.32E-02	2.29E-01
Bladder cancer	2C94	Bladder tissue	2.47E-02	1.44E-01	8.00E-01
Breast cancer	2C60-2C6Z	Breast tissue	5.82E-01	-2.05E-03	-2.90E-03
Cardioembolic stroke	8B11.20	Whole blood	2.63E-04	-3.17E-01	-1.20E+00
Cervical cancer	2C77	Cervical tissue	4.41E-03	4.84E-01	8.33E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	5.23E-01	-1.91E-01	-2.20E-01
Chronic hepatitis C	1E51.1	Whole blood	8.36E-01	6.07E-02	1.93E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	4.98E-01	1.27E-01	2.86E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	5.82E-01	-4.32E-02	-1.09E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	1.52E-01	6.73E-01	1.30E+00
Colon cancer	2B90	Colon tissue	4.31E-10	-2.76E-01	-6.06E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	3.15E-01	1.02E+00	6.29E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	6.07E-01	1.05E-01	1.19E-01
Endometriosis	GA10	Endometrium tissue	9.16E-02	-7.70E-01	-5.49E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	9.94E-01	3.17E-02	8.30E-02
Familial hypercholesterolemia	5C80.00	Whole blood	1.61E-04	7.07E-01	1.35E+00
Gastric cancer	2B72	Gastric tissue	1.00E+00	1.37E-01	1.07E-01
Glioblastopma	2A00.00	Nervous tissue	5.57E-17	3.29E-01	4.49E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	2.75E-01	1.98E-01	2.28E-01
Head and neck cancer	2D42	Head and neck tissue	1.13E-50	9.90E-01	2.87E+00
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	9.60E-01	2.66E-01	2.40E-01
Huntington's disease	8A01.10	Whole blood	5.67E-01	-1.64E-01	-4.98E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	3.16E-01	8.08E-02	1.82E-01
Immunodeficiency	4A00-4A20	Peripheral blood	2.37E-01	-1.90E-01	-4.93E-01
Influenza	1.00E+30	Whole blood	9.59E-03	-1.77E+00	-3.11E+00
Interstitial cystitis	GC00.3	Bladder tissue	9.94E-01	-5.22E-02	-2.36E-01
Intracranial aneurysm	8B01.0	Intracranial artery	2.11E-02	-1.13E+00	-1.45E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.87E-01	6.05E-02	2.32E-01
Ischemic stroke	8B11	Peripheral blood	5.17E-01	-1.53E-01	-2.97E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	1.77E-02	3.36E-02	5.28E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	1.63E-01	-2.63E-01	-3.45E-01
Lateral sclerosis	8B60.4	Skin	7.09E-01	-2.42E-01	-7.05E-01
Liver cancer	2C12.0	Liver tissue	4.73E-03	-3.18E-01	-5.20E-01
Liver failure	DB99.7-DB99.8	Liver tissue	4.92E-01	-6.87E-03	-1.29E-02
Lung cancer	2C25	Lung tissue	7.00E-71	9.32E-01	2.11E+00
Lupus erythematosus	4A40	Whole blood	9.63E-10	-3.51E-01	-6.40E-01
Major depressive disorder	6A70-6A7Z	Whole blood	9.25E-02	-2.37E-01	-5.88E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	8.66E-01	-2.33E-02	-1.19E-01
Melanoma	2C30	Skin	1.36E-01	1.58E-01	1.83E-01
Multiple myeloma	2A83.1	Bone marrow	6.16E-01	8.84E-02	2.09E-01
Multiple myeloma	2A83.1	Peripheral blood	4.16E-01	-1.93E-02	-5.88E-02
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	5.23E-01	3.78E-02	1.04E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.55E-03	3.17E-01	5.56E-01
Myelofibrosis	2A20.2	Whole blood	5.58E-01	-2.97E-01	-4.72E-01
Myocardial infarction	BA41-BA50	Peripheral blood	2.08E-02	-1.06E-01	-1.63E-01
Myopathy	8C70.6	Muscle tissue	3.41E-02	7.66E-01	1.14E+00
Neonatal sepsis	KA60	Whole blood	1.20E-16	-9.95E-01	-1.31E+00
Neuroectodermal tumour	2A00.11	Brain stem tissue	4.46E-07	2.25E+00	3.63E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	4.07E-02	-5.34E-01	-1.28E+00
Obesity related type 2 diabetes	5A11	Omental adipose tissue	1.40E-01	1.35E-01	4.29E-01
Olive pollen allergy	CA08.00	Peripheral blood	2.00E-02	-9.25E-01	-1.83E+00
Oral cancer	2B6E	Oral tissue	2.55E-07	9.70E-01	1.11E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.29E-01	-5.22E-01	-5.63E-01
Osteoporosis	FB83.1	Bone marrow	2.69E-02	-1.15E+00	-1.44E+00
Ovarian cancer	2C73	Ovarian tissue	2.03E-03	9.95E-01	1.50E+00
Pancreatic cancer	2C10	Pancreas	1.63E-03	7.84E-01	9.46E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	1.06E-03	6.89E-01	1.46E+00
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.73E-02	-3.25E-01	-7.30E-01
Pituitary cancer	2D12	Pituitary tissue	9.74E-01	-1.74E-02	-3.20E-02
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.81E-01	2.74E-01	4.41E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	5.39E-01	1.06E-01	2.44E-01
Polycythemia vera	2A20.4	Whole blood	3.55E-01	-3.05E-01	-4.92E-01
Pompe disease	5C51.3	Biceps muscle	9.80E-06	9.02E-01	2.40E+00
Preterm birth	KA21.4Z	Myometrium	1.47E-01	-9.19E-01	-9.32E-01
Prostate cancer	2C82	Prostate	2.03E-02	-8.23E-02	-1.18E-01
Psoriasis	EA90	Skin	2.37E-04	-2.24E-01	-3.76E-01
Rectal cancer	2B92	Rectal colon tissue	4.10E-01	7.90E-02	2.15E-01
Renal cancer	2C90-2C91	Kidney	7.39E-04	-1.74E+00	-1.66E+00
Retinoblastoma	2D02.2	Uvea	6.84E-04	4.39E-01	9.34E-01
Rheumatoid arthritis	FA20	Synovial tissue	6.87E-01	2.10E-01	3.23E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	4.31E-01	9.39E-02	2.85E-01
Schizophrenia	6A20	Prefrontal cortex	7.48E-01	-9.61E-02	-2.55E-01
Schizophrenia	6A20	Superior temporal cortex	1.69E-02	4.36E-01	1.07E+00
Scleroderma	4A42.Z	Whole blood	7.56E-03	-2.93E-01	-1.25E+00
Seizure	8A60-8A6Z	Whole blood	2.04E-01	3.71E-01	5.50E-01
Sensitive skin	EK0Z	Skin	4.02E-01	8.73E-02	3.36E-01
Sepsis with septic shock	1G41	Whole blood	1.32E-34	-1.01E+00	-1.60E+00
Shwachman-Diamond syndrome	3A70.0	Bone marrow	8.01E-01	-8.76E-01	-7.98E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	6.00E-03	-1.56E+00	-1.23E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.80E-01	-1.44E-01	-1.31E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	7.68E-01	2.26E-01	3.36E-01
Skin cancer	2C30-2C3Z	Skin	1.75E-23	6.75E-01	9.73E-01
Thrombocythemia	3B63	Whole blood	2.49E-01	-2.74E-01	-4.38E-01
Thrombocytopenia	3B64	Whole blood	3.68E-01	-3.07E-01	-3.43E-01
Thyroid cancer	2D10	Thyroid	4.59E-17	-5.03E-01	-9.22E-01
Tibial muscular dystrophy	8C75	Muscle tissue	8.55E-01	-1.37E-01	-1.25E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	8.25E-01	-1.69E-01	-7.71E-01
Type 2 diabetes	5A11	Liver tissue	2.03E-01	1.94E-01	8.28E-01
Ureter cancer	2C92	Urothelium	1.09E-01	2.51E-01	9.88E-01
Uterine cancer	2C78	Endometrium tissue	5.84E-01	-1.42E-01	-1.23E-01
Vitiligo	ED63.0	Skin	2.93E-02	6.44E-01	1.62E+00