Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DT9IDPW)

• DTP Name: Organic cation transporter 2 (SLC22A2) DTP Info
• Gene Name: `OCT2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	6.67E-01	2.80E-02	1.41E-01
Adrenocortical carcinoma	2D11.Z	Kidney	3.12E-01	-1.13E-01	-3.96E-01
Alopecia	ED70	Skin from scalp	3.58E-01	-5.53E-02	-1.72E-01
Alzheimer's disease	8A20	Entorhinal cortex	8.22E-01	-1.05E-02	-3.83E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	3.27E-01	1.05E-01	7.75E-01
Aortic stenosis	BB70	Calcified aortic valve	8.90E-01	4.65E-02	6.11E-02
Apnea	7A40	Hyperplastic tonsil	7.55E-01	-1.34E-01	-3.30E-01
Arthropathy	FA00-FA5Z	Peripheral blood	4.51E-01	2.90E-02	1.63E-01
Asthma	CA23	Nasal and bronchial airway	2.12E-01	-6.43E-02	-1.72E-01
Atopic dermatitis	EA80	Skin	1.18E-05	1.40E-01	1.17E+00
Autism	6A02	Whole blood	5.77E-02	-3.60E-02	-1.33E-01
Autoimmune uveitis	9A96	Peripheral monocyte	5.43E-01	-8.39E-02	-3.75E-01
Autosomal dominant monocytopenia	4B04	Whole blood	7.19E-01	2.02E-03	1.13E-02
Bacterial infection of gingival	1C1H	Gingival tissue	4.69E-01	2.14E-02	5.56E-02
Batten disease	5C56.1	Whole blood	9.04E-01	-1.07E-03	-4.69E-03
Behcet's disease	4A62	Peripheral blood	2.08E-01	1.07E-01	4.48E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	2.94E-01	-1.32E-01	-6.00E-01
Bladder cancer	2C94	Bladder tissue	3.51E-07	9.93E-01	5.66E+00
Breast cancer	2C60-2C6Z	Breast tissue	1.47E-23	-2.36E-01	-6.34E-01
Cardioembolic stroke	8B11.20	Whole blood	2.03E-01	-6.29E-02	-2.41E-01
Cervical cancer	2C77	Cervical tissue	9.74E-01	2.13E-02	8.79E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	5.26E-01	4.21E-02	1.75E-01
Chronic hepatitis C	1E51.1	Whole blood	6.14E-01	-1.20E-02	-4.60E-02
Chronic obstructive pulmonary disease	CA22	Lung tissue	8.05E-03	4.99E-02	2.72E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	3.96E-01	5.18E-02	2.24E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	7.50E-02	1.86E-01	1.00E+00
Colon cancer	2B90	Colon tissue	6.58E-02	-6.35E-02	-1.87E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	6.97E-01	-1.89E-02	-1.11E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	4.05E-01	-2.25E-01	-1.17E+00
Endometriosis	GA10	Endometrium tissue	3.28E-02	3.87E-01	9.77E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.70E-01	-2.57E-02	-1.46E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.17E-01	-8.16E-02	-3.36E-01
Gastric cancer	2B72	Gastric tissue	4.93E-02	-2.74E-01	-2.18E+00
Glioblastopma	2A00.00	Nervous tissue	2.46E-01	-1.05E-02	-2.65E-02
Glioma	2A00.0Y-2A00.0Z	White matter tissue	3.40E-02	-1.56E-01	-4.03E-01
Head and neck cancer	2D42	Head and neck tissue	4.80E-01	-3.49E-02	-1.60E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	4.83E-02	-1.08E-01	-4.40E-01
Huntington's disease	8A01.10	Whole blood	9.80E-01	4.68E-02	3.86E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	6.77E-01	-2.64E-02	-8.74E-02
Immunodeficiency	4A00-4A20	Peripheral blood	6.67E-01	-7.45E-02	-6.44E-01
Influenza	1.00E+30	Whole blood	7.59E-02	2.22E-01	3.15E+00
Interstitial cystitis	GC00.3	Bladder tissue	7.84E-01	1.25E-01	5.11E-01
Intracranial aneurysm	8B01.0	Intracranial artery	5.59E-01	-1.40E-01	-3.00E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	8.19E-01	-6.70E-03	-2.10E-02
Ischemic stroke	8B11	Peripheral blood	7.72E-02	1.04E-01	6.36E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	6.66E-01	1.95E-02	7.01E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	6.47E-01	1.03E-01	3.16E-01
Lateral sclerosis	8B60.4	Skin	2.25E-02	2.13E-01	2.22E+00
Liver cancer	2C12.0	Liver tissue	4.08E-06	-2.73E-01	-8.80E-01
Liver failure	DB99.7-DB99.8	Liver tissue	7.25E-01	-2.44E-02	-1.50E-01
Lung cancer	2C25	Lung tissue	6.98E-01	-1.97E-02	-8.16E-02
Lupus erythematosus	4A40	Whole blood	3.96E-01	-4.99E-02	-7.30E-02
Major depressive disorder	6A70-6A7Z	Whole blood	5.48E-01	1.84E-02	6.21E-02
Major depressive disorder	6A70-6A7Z	Hippocampus	2.69E-01	1.83E-02	7.94E-02
Melanoma	2C30	Skin	9.07E-01	1.59E-01	2.18E-01
Multiple myeloma	2A83.1	Bone marrow	1.35E-02	-4.34E-01	-1.22E+00
Multiple myeloma	2A83.1	Peripheral blood	5.18E-01	2.56E-02	9.96E-02
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	4.95E-01	-1.32E-01	-3.77E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	3.63E-01	1.04E-01	4.06E-01
Myelofibrosis	2A20.2	Whole blood	5.05E-01	1.18E-01	8.35E-01
Myocardial infarction	BA41-BA50	Peripheral blood	3.97E-01	3.24E-01	3.34E-01
Myopathy	8C70.6	Muscle tissue	9.84E-02	-1.78E-01	-1.07E+00
Neonatal sepsis	KA60	Whole blood	4.92E-03	-9.29E-02	-4.35E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.20E-04	-6.15E-01	-1.91E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	4.75E-01	5.28E-03	2.81E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	2.79E-01	2.84E-02	2.87E-01
Olive pollen allergy	CA08.00	Peripheral blood	5.85E-02	6.76E-02	1.50E+00
Oral cancer	2B6E	Oral tissue	1.74E-02	-5.79E-01	-1.23E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	9.41E-01	5.60E-02	2.13E-01
Osteoporosis	FB83.1	Bone marrow	1.21E-01	7.60E-02	7.08E-01
Ovarian cancer	2C73	Ovarian tissue	1.74E-01	-5.94E-02	-3.19E-01
Pancreatic cancer	2C10	Pancreas	2.36E-02	-3.65E-01	-7.81E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	1.57E-01	-2.96E-01	-1.02E+00
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.40E-01	-6.95E-02	-2.29E-01
Pituitary cancer	2D12	Pituitary tissue	8.03E-01	6.88E-02	1.35E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	6.97E-01	6.86E-02	1.45E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	6.98E-01	5.10E-02	3.32E-01
Polycythemia vera	2A20.4	Whole blood	2.01E-01	1.31E-03	8.10E-03
Pompe disease	5C51.3	Biceps muscle	8.86E-01	7.01E-02	3.12E-01
Preterm birth	KA21.4Z	Myometrium	9.33E-01	1.28E-01	9.88E-01
Prostate cancer	2C82	Prostate	4.25E-01	-2.07E-01	-3.53E-01
Psoriasis	EA90	Skin	5.61E-04	-1.80E-01	-4.16E-01
Rectal cancer	2B92	Rectal colon tissue	3.66E-01	-2.05E-01	-7.46E-01
Renal cancer	2C90-2C91	Kidney	3.37E-02	-1.25E+00	-7.79E-01
Retinoblastoma	2D02.2	Uvea	4.51E-05	-6.63E-01	-3.08E+00
Rheumatoid arthritis	FA20	Synovial tissue	9.68E-01	-1.20E-02	-5.67E-02
Rhinovirus infection	CA42.1	Nasal epithelium tissue	6.84E-01	-3.03E-02	-1.89E-01
Schizophrenia	6A20	Prefrontal cortex	7.23E-01	1.76E-02	3.79E-02
Schizophrenia	6A20	Superior temporal cortex	3.97E-01	-2.51E-02	-2.54E-01
Scleroderma	4A42.Z	Whole blood	1.88E-01	-8.54E-02	-3.25E-01
Seizure	8A60-8A6Z	Whole blood	7.73E-01	1.22E-02	6.09E-02
Sensitive skin	EK0Z	Skin	5.81E-01	-2.94E-02	-1.79E-01
Sepsis with septic shock	1G41	Whole blood	5.52E-04	1.22E-01	4.70E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	2.40E-01	4.76E-01	1.13E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.34E-01	2.21E-01	1.13E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	8.74E-01	2.50E-02	1.91E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.26E-01	-6.25E-03	-6.30E-02
Skin cancer	2C30-2C3Z	Skin	1.45E-01	1.37E-01	3.17E-01
Thrombocythemia	3B63	Whole blood	4.14E-05	1.39E-01	9.50E-01
Thrombocytopenia	3B64	Whole blood	9.54E-01	5.18E-03	1.08E-02
Thyroid cancer	2D10	Thyroid	1.17E-02	2.81E-02	8.16E-02
Tibial muscular dystrophy	8C75	Muscle tissue	6.44E-01	-7.45E-02	-3.85E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	3.58E-01	7.04E-02	2.47E+00
Type 2 diabetes	5A11	Liver tissue	4.35E-01	-1.55E-01	-8.93E-01
Ureter cancer	2C92	Urothelium	1.92E-01	6.24E-02	2.47E-01
Uterine cancer	2C78	Endometrium tissue	3.22E-01	-5.13E-03	-1.30E-02
Vitiligo	ED63.0	Skin	4.52E-02	-6.81E-02	-6.37E-01