Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTBGZ8H)

• DTP Name: Excitatory amino acid transporter 5 (SLC1A7) DTP Info
• Gene Name: EAAT5

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	8.18E-05	-6.99E-02	-2.48E-01
Adrenocortical carcinoma	2D11.Z	Kidney	1.88E-01	-1.12E-01	-5.43E-01
Alopecia	ED70	Skin from scalp	6.20E-02	-5.07E-02	-1.88E-01
Alzheimer's disease	8A20	Entorhinal cortex	3.40E-04	1.19E-01	3.91E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	9.14E-01	-1.19E-01	-1.69E-01
Aortic stenosis	BB70	Calcified aortic valve	5.48E-01	-9.75E-02	-2.97E-01
Apnea	7A40	Hyperplastic tonsil	5.29E-01	-1.48E-01	-7.09E-01
Arthropathy	FA00-FA5Z	Peripheral blood	3.98E-01	-4.08E-03	-1.23E-02
Asthma	CA23	Nasal and bronchial airway	6.90E-03	-1.62E-01	-4.39E-01
Atopic dermatitis	EA80	Skin	7.31E-02	6.03E-02	4.83E-01
Autism	6A02	Whole blood	4.84E-01	-1.04E-01	-3.39E-01
Autoimmune uveitis	9A96	Peripheral monocyte	9.03E-02	-1.11E-01	-7.90E-01
Autosomal dominant monocytopenia	4B04	Whole blood	5.52E-01	-1.35E-02	-7.04E-02
Bacterial infection of gingival	1C1H	Gingival tissue	1.10E-01	7.44E-02	3.22E-01
Batten disease	5C56.1	Whole blood	9.56E-02	3.33E-01	1.02E+00
Behcet's disease	4A62	Peripheral blood	1.89E-01	-3.53E-01	-7.39E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	7.00E-01	-7.11E-02	-3.37E-01
Bladder cancer	2C94	Bladder tissue	2.16E-05	6.05E-01	3.38E+00
Breast cancer	2C60-2C6Z	Breast tissue	1.48E-20	-2.27E-01	-6.40E-01
Cardioembolic stroke	8B11.20	Whole blood	5.67E-01	2.11E-02	1.04E-01
Cervical cancer	2C77	Cervical tissue	3.63E-01	1.66E-01	5.78E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	3.15E-01	-6.55E-02	-2.73E-01
Chronic hepatitis C	1E51.1	Whole blood	8.39E-01	4.84E-03	2.42E-02
Chronic obstructive pulmonary disease	CA22	Lung tissue	4.13E-01	4.58E-02	2.05E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	2.28E-03	9.81E-02	4.79E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	9.26E-01	-2.34E-02	-1.17E-01
Colon cancer	2B90	Colon tissue	6.82E-08	-1.65E-02	-3.52E-02
Coronary artery disease	BA80-BA8Z	Peripheral blood	4.94E-01	-1.03E-01	-6.63E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	2.11E-01	-1.26E-01	-1.53E+00
Endometriosis	GA10	Endometrium tissue	4.24E-01	7.08E-02	2.99E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	3.08E-01	-1.39E-01	-5.01E-01
Familial hypercholesterolemia	5C80.00	Whole blood	9.55E-03	-1.56E-01	-6.42E-01
Gastric cancer	2B72	Gastric tissue	6.73E-01	1.77E-01	3.28E-01
Glioblastopma	2A00.00	Nervous tissue	1.86E-01	-7.15E-02	-2.52E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	1.20E-06	-5.16E-01	-3.43E+00
Head and neck cancer	2D42	Head and neck tissue	3.61E-01	2.54E-02	1.02E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	9.24E-01	-9.83E-02	-4.65E-01
Huntington's disease	8A01.10	Whole blood	6.25E-01	5.97E-02	2.09E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	9.90E-02	8.10E-02	4.17E-01
Immunodeficiency	4A00-4A20	Peripheral blood	5.84E-01	7.97E-02	6.21E-01
Influenza	1.00E+30	Whole blood	9.70E-02	1.77E-01	1.81E+00
Interstitial cystitis	GC00.3	Bladder tissue	4.40E-01	6.38E-03	1.23E-01
Intracranial aneurysm	8B01.0	Intracranial artery	1.81E-01	-6.59E-02	-3.08E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	3.84E-01	5.34E-04	2.95E-03
Ischemic stroke	8B11	Peripheral blood	7.51E-01	-5.71E-02	-1.53E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	7.60E-02	5.06E-02	1.74E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	5.25E-01	7.94E-02	2.85E-01
Lateral sclerosis	8B60.4	Skin	1.93E-01	1.02E-01	6.03E-01
Liver cancer	2C12.0	Liver tissue	5.80E-01	-2.02E-01	-4.30E-01
Liver failure	DB99.7-DB99.8	Liver tissue	3.12E-03	5.56E-01	1.56E+00
Lung cancer	2C25	Lung tissue	2.99E-15	-8.61E-02	-2.60E-01
Lupus erythematosus	4A40	Whole blood	1.21E-02	-1.07E-01	-3.04E-01
Major depressive disorder	6A70-6A7Z	Whole blood	9.89E-01	-5.83E-02	-2.22E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	8.94E-01	-1.18E-02	-6.20E-02
Melanoma	2C30	Skin	6.96E-01	-2.54E-02	-7.28E-02
Multiple myeloma	2A83.1	Bone marrow	5.51E-02	-1.77E-01	-6.04E-01
Multiple myeloma	2A83.1	Peripheral blood	2.08E-01	5.45E-02	2.99E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	8.78E-01	-1.75E-02	-8.84E-02
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.64E-01	2.18E-04	1.26E-03
Myelofibrosis	2A20.2	Whole blood	2.36E-03	1.85E-01	1.49E+00
Myocardial infarction	BA41-BA50	Peripheral blood	6.48E-03	3.12E-01	7.89E-01
Myopathy	8C70.6	Muscle tissue	9.76E-02	3.30E-01	5.90E-01
Neonatal sepsis	KA60	Whole blood	4.18E-02	-3.29E-02	-1.27E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	7.04E-01	-2.18E-01	-7.71E-01
Non-alcoholic fatty liver disease	DB92	Liver tissue	1.63E-01	-3.89E-02	-2.68E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	5.39E-03	2.23E-01	1.73E+00
Olive pollen allergy	CA08.00	Peripheral blood	1.60E-02	2.02E-01	1.75E+00
Oral cancer	2B6E	Oral tissue	4.81E-06	-4.08E-01	-1.08E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	5.75E-01	-4.98E-02	-1.46E-01
Osteoporosis	FB83.1	Bone marrow	6.45E-01	6.74E-02	3.37E-01
Ovarian cancer	2C73	Ovarian tissue	1.68E-01	-7.16E-02	-1.89E-01
Pancreatic cancer	2C10	Pancreas	1.07E-01	1.20E-01	3.60E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	1.95E-01	-6.56E-02	-4.03E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	9.48E-02	-9.42E-02	-2.91E-01
Pituitary cancer	2D12	Pituitary tissue	2.70E-01	2.25E-02	1.06E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.33E-01	-1.54E-01	-6.82E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	2.69E-01	6.45E-02	4.17E-01
Polycythemia vera	2A20.4	Whole blood	9.86E-07	1.60E-01	1.43E+00
Pompe disease	5C51.3	Biceps muscle	8.58E-01	-6.96E-03	-3.84E-02
Preterm birth	KA21.4Z	Myometrium	9.60E-01	-3.48E-02	-1.36E-01
Prostate cancer	2C82	Prostate	2.62E-01	8.32E-02	2.45E-01
Psoriasis	EA90	Skin	8.61E-01	3.78E-03	1.57E-02
Rectal cancer	2B92	Rectal colon tissue	3.93E-02	1.78E-01	5.88E-01
Renal cancer	2C90-2C91	Kidney	1.44E-01	-7.79E-02	-3.52E-01
Retinoblastoma	2D02.2	Uvea	7.37E-12	-4.06E+00	-2.26E+01
Rheumatoid arthritis	FA20	Synovial tissue	5.02E-02	-3.08E-01	-7.99E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	8.74E-01	2.67E-02	2.11E-01
Schizophrenia	6A20	Prefrontal cortex	6.47E-01	7.42E-02	1.83E-01
Schizophrenia	6A20	Superior temporal cortex	7.41E-01	2.03E-02	1.64E-01
Scleroderma	4A42.Z	Whole blood	2.19E-01	-1.38E-01	-7.82E-01
Seizure	8A60-8A6Z	Whole blood	4.05E-01	4.49E-02	1.95E-01
Sensitive skin	EK0Z	Skin	7.19E-01	8.78E-02	7.30E-01
Sepsis with septic shock	1G41	Whole blood	4.05E-01	7.06E-03	2.56E-02
Shwachman-Diamond syndrome	3A70.0	Bone marrow	9.46E-01	-3.66E-02	-2.28E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	4.70E-01	1.62E-02	1.01E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.56E-01	8.54E-02	3.64E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	2.55E-01	-1.66E-01	-1.27E+00
Skin cancer	2C30-2C3Z	Skin	4.66E-16	-1.78E-01	-6.46E-01
Thrombocythemia	3B63	Whole blood	1.37E-02	1.70E-01	1.46E+00
Thrombocytopenia	3B64	Whole blood	6.28E-01	2.39E-02	6.54E-02
Thyroid cancer	2D10	Thyroid	5.35E-02	-4.93E-02	-2.01E-01
Tibial muscular dystrophy	8C75	Muscle tissue	4.09E-02	-3.26E-01	-6.92E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	1.35E-01	2.64E-01	1.53E+00
Type 2 diabetes	5A11	Liver tissue	4.18E-02	-1.59E-01	-1.61E+00
Ureter cancer	2C92	Urothelium	5.60E-01	2.68E-02	9.03E-02
Uterine cancer	2C78	Endometrium tissue	1.57E-02	4.05E-02	1.59E-01
Vitiligo	ED63.0	Skin	6.21E-01	9.41E-03	3.32E-02