Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTJ4NEG)

• DTP Name: ATP-binding cassette sub-family A member 2 (ABCA2) DTP Info
• Gene Name: ABCA2

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	2.16E-26	2.70E-01	1.16E+00
Adrenocortical carcinoma	2D11.Z	Kidney	4.47E-01	4.66E-02	1.23E-01
Alopecia	ED70	Skin from scalp	1.55E-01	-6.53E-02	-2.17E-01
Alzheimer's disease	8A20	Entorhinal cortex	2.47E-01	8.02E-02	1.35E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	7.65E-01	-8.35E-03	-6.39E-02
Aortic stenosis	BB70	Calcified aortic valve	9.64E-01	-3.62E-02	-5.81E-02
Apnea	7A40	Hyperplastic tonsil	3.07E-01	-6.41E-02	-3.22E-01
Arthropathy	FA00-FA5Z	Peripheral blood	3.10E-01	-6.08E-02	-2.57E-01
Asthma	CA23	Nasal and bronchial airway	2.02E-01	-4.77E-02	-1.45E-01
Atopic dermatitis	EA80	Skin	4.26E-01	-3.64E-02	-1.26E-01
Autism	6A02	Whole blood	2.97E-01	1.25E-01	3.86E-01
Autoimmune uveitis	9A96	Peripheral monocyte	8.59E-01	5.08E-02	6.62E-01
Autosomal dominant monocytopenia	4B04	Whole blood	7.66E-01	-2.66E-02	-1.92E-01
Bacterial infection of gingival	1C1H	Gingival tissue	7.52E-03	1.72E-01	5.76E-01
Batten disease	5C56.1	Whole blood	9.38E-01	6.97E-03	3.67E-02
Behcet's disease	4A62	Peripheral blood	8.19E-01	-1.95E-01	-5.30E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	9.52E-01	-3.10E-02	-1.15E-01
Bladder cancer	2C94	Bladder tissue	1.40E-01	5.05E-01	1.19E+00
Breast cancer	2C60-2C6Z	Breast tissue	1.79E-02	5.43E-02	1.17E-01
Cardioembolic stroke	8B11.20	Whole blood	3.91E-07	-4.00E-01	-1.98E+00
Cervical cancer	2C77	Cervical tissue	1.42E-01	-1.37E-02	-8.18E-02
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	9.34E-01	1.19E-01	2.76E-01
Chronic hepatitis C	1E51.1	Whole blood	6.31E-01	3.15E-02	1.97E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	5.45E-01	2.74E-02	8.44E-02
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	8.88E-02	1.49E-01	3.06E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	4.79E-01	2.10E-02	9.61E-02
Colon cancer	2B90	Colon tissue	7.43E-06	-1.41E-01	-4.52E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	2.01E-01	-3.15E-02	-3.82E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	9.63E-01	-2.91E-02	-1.18E-01
Endometriosis	GA10	Endometrium tissue	6.40E-02	-4.21E-02	-1.24E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	1.61E-01	-3.78E-02	-3.85E-01
Familial hypercholesterolemia	5C80.00	Whole blood	2.63E-02	-1.60E-01	-5.86E-01
Gastric cancer	2B72	Gastric tissue	6.05E-01	-5.72E-02	-8.69E-02
Glioblastopma	2A00.00	Nervous tissue	5.53E-106	-2.42E+00	-1.92E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	3.73E-06	-9.14E-01	-2.82E+00
Head and neck cancer	2D42	Head and neck tissue	7.10E-03	-2.94E-02	-8.32E-02
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	8.97E-02	2.21E-01	3.13E-01
Huntington's disease	8A01.10	Whole blood	3.91E-01	7.97E-02	5.06E-01
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	4.60E-02	8.93E-02	7.40E-01
Immunodeficiency	4A00-4A20	Peripheral blood	3.12E-01	8.36E-03	8.15E-02
Influenza	1.00E+30	Whole blood	8.91E-02	3.12E-01	2.39E+00
Interstitial cystitis	GC00.3	Bladder tissue	9.87E-01	1.76E-02	4.93E-02
Intracranial aneurysm	8B01.0	Intracranial artery	6.10E-01	-1.49E-01	-4.94E-01
Irritable bowel syndrome	DD91.0	Rectal colon tissue	1.41E-01	-4.49E-02	-2.36E-01
Ischemic stroke	8B11	Peripheral blood	6.83E-01	1.04E-01	3.20E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	7.44E-02	-9.80E-02	-3.58E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	2.62E-01	-7.76E-03	-2.67E-02
Lateral sclerosis	8B60.4	Skin	6.69E-01	5.76E-02	1.21E-01
Liver cancer	2C12.0	Liver tissue	5.33E-01	-6.17E-02	-1.55E-01
Liver failure	DB99.7-DB99.8	Liver tissue	2.81E-03	1.89E-01	1.15E+00
Lung cancer	2C25	Lung tissue	4.90E-09	-1.53E-01	-6.05E-01
Lupus erythematosus	4A40	Whole blood	5.33E-01	2.10E-02	5.09E-02
Major depressive disorder	6A70-6A7Z	Whole blood	3.21E-01	-2.86E-02	-1.36E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	5.50E-01	8.74E-02	3.02E-01
Melanoma	2C30	Skin	1.86E-02	-4.44E-01	-8.73E-01
Multiple myeloma	2A83.1	Bone marrow	2.01E-01	9.88E-02	4.53E-01
Multiple myeloma	2A83.1	Peripheral blood	5.55E-01	6.96E-02	2.79E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	2.82E-01	-1.12E-01	-4.36E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	8.64E-01	-5.42E-02	-3.46E-01
Myelofibrosis	2A20.2	Whole blood	7.34E-01	-1.07E-02	-8.01E-02
Myocardial infarction	BA41-BA50	Peripheral blood	3.80E-01	-1.70E-01	-3.40E-01
Myopathy	8C70.6	Muscle tissue	1.89E-01	-2.05E-01	-9.33E-01
Neonatal sepsis	KA60	Whole blood	1.41E-01	4.65E-02	1.45E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	3.82E-08	-3.80E+00	-5.50E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	2.62E-01	1.05E-01	8.83E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	2.56E-01	8.72E-03	1.09E-01
Olive pollen allergy	CA08.00	Peripheral blood	3.03E-02	3.20E-01	1.76E+00
Oral cancer	2B6E	Oral tissue	5.17E-12	-4.14E-01	-2.15E+00
Osteoarthritis	FA00-FA0Z	Synovial tissue	4.99E-01	-3.57E-01	-8.42E-01
Osteoporosis	FB83.1	Bone marrow	7.37E-04	1.25E+00	3.93E+00
Ovarian cancer	2C73	Ovarian tissue	4.26E-01	4.50E-02	1.23E-01
Pancreatic cancer	2C10	Pancreas	4.45E-01	-1.93E-02	-5.72E-02
Parkinson's disease	8A00.0	Substantia nigra tissue	7.92E-01	9.37E-02	1.99E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	5.43E-04	-2.58E-01	-1.03E+00
Pituitary cancer	2D12	Pituitary tissue	5.09E-04	7.04E-01	1.68E+00
Pituitary gonadotrope tumour	2D12	Pituitary tissue	4.14E-04	8.12E-01	2.10E+00
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	6.18E-01	1.60E-02	6.53E-02
Polycythemia vera	2A20.4	Whole blood	7.95E-01	-4.07E-02	-3.58E-01
Pompe disease	5C51.3	Biceps muscle	8.64E-01	2.60E-02	1.92E-01
Preterm birth	KA21.4Z	Myometrium	3.46E-01	9.47E-02	8.50E-01
Prostate cancer	2C82	Prostate	4.54E-02	2.19E-01	6.17E-01
Psoriasis	EA90	Skin	8.83E-01	9.63E-02	2.39E-01
Rectal cancer	2B92	Rectal colon tissue	6.09E-01	1.29E-01	3.97E-01
Renal cancer	2C90-2C91	Kidney	3.38E-01	-3.43E-01	-6.60E-01
Retinoblastoma	2D02.2	Uvea	1.65E-09	-8.32E-01	-4.23E+00
Rheumatoid arthritis	FA20	Synovial tissue	3.10E-01	-1.09E-01	-2.24E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	2.48E-01	-4.03E-02	-2.30E-01
Schizophrenia	6A20	Prefrontal cortex	6.65E-02	-1.23E-01	-1.91E-01
Schizophrenia	6A20	Superior temporal cortex	2.73E-01	-1.02E-01	-2.21E-01
Scleroderma	4A42.Z	Whole blood	1.53E-01	-1.26E-01	-4.53E-01
Seizure	8A60-8A6Z	Whole blood	5.00E-01	9.00E-02	3.87E-01
Sensitive skin	EK0Z	Skin	9.53E-01	-4.58E-02	-1.76E-01
Sepsis with septic shock	1G41	Whole blood	3.34E-05	1.46E-01	4.63E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	6.93E-01	8.68E-02	5.52E-01
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.84E-01	6.63E-02	2.72E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	9.31E-01	-6.74E-02	-1.36E+00
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.45E-02	-4.34E-01	-2.71E+00
Skin cancer	2C30-2C3Z	Skin	8.40E-01	-1.61E-02	-4.71E-02
Thrombocythemia	3B63	Whole blood	4.43E-01	-4.35E-02	-3.28E-01
Thrombocytopenia	3B64	Whole blood	5.40E-01	4.61E-01	4.69E-01
Thyroid cancer	2D10	Thyroid	1.39E-06	-2.98E-01	-5.66E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.31E-03	-4.07E-01	-8.45E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	5.11E-01	-6.49E-01	-1.88E+00
Type 2 diabetes	5A11	Liver tissue	6.59E-01	-3.74E-02	-1.14E-01
Ureter cancer	2C92	Urothelium	9.68E-02	9.96E-02	3.89E-01
Uterine cancer	2C78	Endometrium tissue	1.04E-04	-2.23E-01	-5.65E-01
Vitiligo	ED63.0	Skin	3.75E-01	-7.35E-02	-5.34E-01