Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTSYQGK)

• DTP Name: Multidrug resistance-associated protein 1 (ABCC1) DTP Info
• Gene Name: MRP1

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	8.56E-36	6.27E-01	1.80E+00
Adrenocortical carcinoma	2D11.Z	Kidney	2.93E-06	5.19E-01	1.66E+00
Alopecia	ED70	Skin from scalp	3.46E-04	-1.40E-01	-8.32E-01
Alzheimer's disease	8A20	Entorhinal cortex	3.12E-01	-1.61E-02	-7.68E-02
Ankylosing spondylitis	FA92.0	Pheripheral blood	8.98E-02	1.33E-01	7.11E-01
Aortic stenosis	BB70	Calcified aortic valve	1.40E-01	-1.41E-01	-5.82E-01
Apnea	7A40	Hyperplastic tonsil	2.85E-01	-4.25E-01	-8.86E-01
Arthropathy	FA00-FA5Z	Peripheral blood	8.27E-01	1.42E-02	7.14E-02
Asthma	CA23	Nasal and bronchial airway	1.34E-04	3.10E-01	6.28E-01
Atopic dermatitis	EA80	Skin	1.04E-06	3.87E-01	1.96E+00
Autism	6A02	Whole blood	5.97E-02	1.65E-01	5.91E-01
Autoimmune uveitis	9A96	Peripheral monocyte	1.81E-01	2.77E-01	1.13E+00
Autosomal dominant monocytopenia	4B04	Whole blood	1.76E-01	-2.28E-01	-3.64E-01
Bacterial infection of gingival	1C1H	Gingival tissue	7.85E-03	-7.73E-02	-2.51E-01
Batten disease	5C56.1	Whole blood	1.51E-01	2.62E-01	1.16E+00
Behcet's disease	4A62	Peripheral blood	2.72E-01	-1.08E-01	-6.06E-01
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	5.91E-01	5.05E-02	3.65E-01
Bladder cancer	2C94	Bladder tissue	6.46E-01	1.04E-01	4.49E-01
Breast cancer	2C60-2C6Z	Breast tissue	1.33E-51	5.67E-01	1.25E+00
Cardioembolic stroke	8B11.20	Whole blood	3.20E-08	-2.35E-01	-1.52E+00
Cervical cancer	2C77	Cervical tissue	3.12E-01	-1.62E-01	-4.67E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	5.74E-01	-2.94E-02	-6.77E-02
Chronic hepatitis C	1E51.1	Whole blood	1.94E-01	-1.57E-01	-6.32E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	2.29E-01	-9.91E-02	-3.13E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	4.36E-01	9.99E-02	1.76E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	2.46E-01	8.06E-02	3.25E-01
Colon cancer	2B90	Colon tissue	7.37E-83	1.18E+00	2.79E+00
Coronary artery disease	BA80-BA8Z	Peripheral blood	1.94E-02	8.17E-01	2.37E+00
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	4.05E-01	-3.36E-01	-6.36E-01
Endometriosis	GA10	Endometrium tissue	1.14E-01	-1.75E-01	-2.98E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	7.96E-02	1.97E-01	1.36E+00
Familial hypercholesterolemia	5C80.00	Whole blood	1.19E-14	7.14E-01	1.96E+00
Gastric cancer	2B72	Gastric tissue	4.46E-01	1.71E-02	2.50E-01
Glioblastopma	2A00.00	Nervous tissue	2.59E-117	5.51E-01	1.85E+00
Glioma	2A00.0Y-2A00.0Z	White matter tissue	3.63E-06	1.04E+00	2.01E+00
Head and neck cancer	2D42	Head and neck tissue	1.78E-08	3.79E-01	7.37E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	1.64E-01	-6.82E-02	-4.02E-01
Huntington's disease	8A01.10	Whole blood	1.05E-01	2.66E-01	1.26E+00
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	6.86E-01	-1.55E-02	-1.02E-01
Immunodeficiency	4A00-4A20	Peripheral blood	1.96E-01	7.49E-02	4.20E-01
Influenza	1.00E+30	Whole blood	9.95E-03	-1.09E+00	-4.47E+00
Interstitial cystitis	GC00.3	Bladder tissue	6.37E-04	4.06E-01	2.74E+00
Intracranial aneurysm	8B01.0	Intracranial artery	1.56E-04	5.40E-01	1.66E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	7.81E-05	1.69E-01	7.86E-01
Ischemic stroke	8B11	Peripheral blood	1.86E-01	7.59E-02	5.27E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	6.54E-02	2.81E-02	1.09E-01
Lateral sclerosis	8B60.4	Cervical spinal cord	1.96E-01	-3.74E-02	-1.61E-01
Lateral sclerosis	8B60.4	Skin	4.28E-01	3.21E-02	7.04E-01
Liver cancer	2C12.0	Liver tissue	5.12E-23	4.83E-01	2.27E+00
Liver failure	DB99.7-DB99.8	Liver tissue	1.26E-07	1.23E+00	4.48E+00
Lung cancer	2C25	Lung tissue	1.90E-30	1.76E-01	7.31E-01
Lupus erythematosus	4A40	Whole blood	6.18E-01	-1.23E-01	-1.77E-01
Major depressive disorder	6A70-6A7Z	Whole blood	6.97E-01	2.69E-02	1.29E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	7.25E-01	2.18E-02	1.51E-01
Melanoma	2C30	Skin	9.59E-01	-1.61E-03	-1.85E-03
Multiple myeloma	2A83.1	Bone marrow	2.70E-03	-2.31E-01	-1.64E+00
Multiple myeloma	2A83.1	Peripheral blood	6.19E-01	9.35E-02	4.62E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.80E-01	1.96E-01	9.51E-01
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	2.47E-01	1.60E-01	4.95E-01
Myelofibrosis	2A20.2	Whole blood	3.79E-03	-2.19E-01	-1.94E+00
Myocardial infarction	BA41-BA50	Peripheral blood	7.48E-01	3.49E-02	3.16E-02
Myopathy	8C70.6	Muscle tissue	9.68E-01	-1.58E-01	-3.24E-01
Neonatal sepsis	KA60	Whole blood	1.66E-01	-2.21E-02	-7.13E-02
Neuroectodermal tumour	2A00.11	Brain stem tissue	2.68E-08	5.65E-01	3.11E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	5.11E-01	1.06E-01	6.93E-01
Obesity related type 2 diabetes	5A11	Omental adipose tissue	3.77E-01	-2.35E-01	-4.78E-01
Olive pollen allergy	CA08.00	Peripheral blood	4.49E-03	-5.38E-01	-2.58E+00
Oral cancer	2B6E	Oral tissue	7.17E-05	5.93E-01	7.85E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	4.27E-01	3.65E-01	2.65E-01
Osteoporosis	FB83.1	Bone marrow	4.50E-01	2.98E-01	1.00E+00
Ovarian cancer	2C73	Ovarian tissue	1.01E-02	8.86E-01	1.34E+00
Pancreatic cancer	2C10	Pancreas	1.59E-02	4.29E-01	6.42E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	3.67E-01	-1.78E-01	-9.02E-01
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	1.43E-01	-4.51E-02	-2.08E-01
Pituitary cancer	2D12	Pituitary tissue	1.32E-01	1.31E-01	3.58E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	2.73E-01	8.94E-02	2.11E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	4.70E-01	4.44E-03	1.55E-02
Polycythemia vera	2A20.4	Whole blood	8.62E-18	-2.79E-01	-2.34E+00
Pompe disease	5C51.3	Biceps muscle	1.30E-02	-5.80E-01	-1.75E+00
Preterm birth	KA21.4Z	Myometrium	2.70E-01	-8.13E-03	-2.91E-02
Prostate cancer	2C82	Prostate	8.18E-07	9.06E-01	1.81E+00
Psoriasis	EA90	Skin	5.41E-31	8.62E-01	2.11E+00
Rectal cancer	2B92	Rectal colon tissue	1.09E-07	1.67E+00	7.60E+00
Renal cancer	2C90-2C91	Kidney	8.37E-06	6.90E-01	2.31E+00
Retinoblastoma	2D02.2	Uvea	1.88E-05	4.71E-01	3.14E+00
Rheumatoid arthritis	FA20	Synovial tissue	3.15E-06	7.81E-01	3.00E+00
Rhinovirus infection	CA42.1	Nasal epithelium tissue	2.23E-01	-4.28E-02	-2.17E-01
Schizophrenia	6A20	Prefrontal cortex	1.98E-01	-1.14E-02	-1.24E-02
Schizophrenia	6A20	Superior temporal cortex	4.62E-01	-5.08E-02	-4.17E-01
Scleroderma	4A42.Z	Whole blood	1.05E-02	2.28E-01	1.68E+00
Seizure	8A60-8A6Z	Whole blood	8.01E-01	6.69E-02	2.82E-01
Sensitive skin	EK0Z	Skin	2.56E-02	1.97E-01	1.71E+00
Sepsis with septic shock	1G41	Whole blood	2.81E-21	-2.79E-01	-9.75E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	7.98E-03	-6.52E-01	-3.66E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	1.31E-02	6.70E-01	1.77E+00
Simpson golabi behmel syndrome	LD2C	Adipose tissue	3.61E-01	5.25E-01	8.84E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	2.09E-01	1.08E-01	6.07E-01
Skin cancer	2C30-2C3Z	Skin	4.74E-11	4.66E-01	7.32E-01
Thrombocythemia	3B63	Whole blood	2.67E-06	-2.44E-01	-2.29E+00
Thrombocytopenia	3B64	Whole blood	8.19E-01	-5.75E-02	-2.33E-01
Thyroid cancer	2D10	Thyroid	1.13E-06	-2.97E-01	-8.71E-01
Tibial muscular dystrophy	8C75	Muscle tissue	1.51E-01	-3.44E-01	-4.04E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	6.55E-01	-4.95E-02	-4.48E-01
Type 2 diabetes	5A11	Liver tissue	3.82E-01	1.16E-01	9.50E-01
Ureter cancer	2C92	Urothelium	5.78E-02	-1.38E-01	-7.56E-01
Uterine cancer	2C78	Endometrium tissue	3.85E-01	2.71E-02	6.12E-02
Vitiligo	ED63.0	Skin	5.68E-01	-1.35E-01	-1.03E+00