Details of the Drug-Related molecule(s) Expression Atlas

General Information of DTP (ID: DTW40Z7)

• DTP Name: Electroneutral sodium bicarbonate exchanger 1 (SLC4A8) DTP Info
• Gene Name: NDCBE

The Expression Level of Molecule(s) in Normal Tissue

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Disease Name	ICD 11	Studied Tissue	p-value	Fold-Change	Z-score
Acute myelocytic leukaemia	2B33.1	Bone marrow	5.21E-04	4.47E-02	3.41E-01
Adrenocortical carcinoma	2D11.Z	Kidney	3.13E-05	6.20E-01	1.51E+00
Alopecia	ED70	Skin from scalp	1.65E-01	7.30E-02	3.10E-01
Alzheimer's disease	8A20	Entorhinal cortex	1.04E-06	-3.71E-01	-6.56E-01
Ankylosing spondylitis	FA92.0	Pheripheral blood	1.27E-01	1.90E-01	3.10E-01
Aortic stenosis	BB70	Calcified aortic valve	8.20E-01	3.44E-02	5.14E-02
Apnea	7A40	Hyperplastic tonsil	5.93E-01	1.12E-01	8.28E-01
Arthropathy	FA00-FA5Z	Peripheral blood	9.21E-01	3.95E-02	2.64E-01
Asthma	CA23	Nasal and bronchial airway	6.59E-04	-2.16E-01	-3.05E-01
Atopic dermatitis	EA80	Skin	1.22E-03	1.27E-01	8.82E-01
Autism	6A02	Whole blood	3.35E-01	-3.05E-02	-1.86E-01
Autoimmune uveitis	9A96	Peripheral monocyte	2.98E-02	3.49E-01	1.83E+00
Autosomal dominant monocytopenia	4B04	Whole blood	1.93E-01	-8.02E-02	-4.83E-01
Bacterial infection of gingival	1C1H	Gingival tissue	1.04E-02	7.40E-02	2.57E-01
Batten disease	5C56.1	Whole blood	3.66E-01	8.46E-02	7.94E-01
Behcet's disease	4A62	Peripheral blood	6.78E-01	-5.32E-05	-4.60E-04
Bipolar disorder	6A60-6A6Z	Prefrontal cortex	6.67E-01	6.81E-02	2.89E-01
Bladder cancer	2C94	Bladder tissue	3.64E-04	4.55E-01	2.07E+00
Breast cancer	2C60-2C6Z	Breast tissue	8.54E-106	6.03E-01	1.86E+00
Cardioembolic stroke	8B11.20	Whole blood	1.15E-01	-7.65E-02	-2.37E-01
Cervical cancer	2C77	Cervical tissue	4.74E-02	-1.04E-01	-4.20E-01
Childhood onset rheumatic disease	FA20.Z	Peripheral blood	1.28E-01	-4.96E-02	-1.49E-01
Chronic hepatitis C	1E51.1	Whole blood	9.53E-01	8.41E-02	3.38E-01
Chronic obstructive pulmonary disease	CA22	Lung tissue	2.49E-02	1.76E-01	8.33E-01
Chronic obstructive pulmonary disease	CA22	Small airway epithelium	3.53E-05	2.51E-01	4.87E-01
Chronic rhinosinusitis	CA0A	Sinus mucosa tissue	6.69E-01	-6.16E-02	-1.70E-01
Colon cancer	2B90	Colon tissue	3.11E-24	1.45E-01	7.73E-01
Coronary artery disease	BA80-BA8Z	Peripheral blood	5.56E-01	-2.14E-01	-7.63E-01
Diffuse large B-cell lymphoma	2A81	Tonsil tissue	8.96E-01	-7.86E-02	-2.69E-01
Endometriosis	GA10	Endometrium tissue	4.16E-01	1.27E-01	4.96E-01
Familial hypercholesterolemia	5C80.00	Peripheral blood	1.12E-01	-7.00E-02	-2.66E-01
Familial hypercholesterolemia	5C80.00	Whole blood	5.57E-01	3.14E-02	1.82E-01
Gastric cancer	2B72	Gastric tissue	3.81E-01	1.82E-02	1.27E-01
Glioblastopma	2A00.00	Nervous tissue	2.07E-38	-5.76E-01	-8.88E-01
Glioma	2A00.0Y-2A00.0Z	White matter tissue	5.98E-01	-2.24E-01	-2.78E-01
Head and neck cancer	2D42	Head and neck tissue	1.23E-12	-3.28E-01	-2.77E-01
HIV-associated neurocognitive impairment	8A2Y-8A2Z	White matter tissue	3.77E-01	7.45E-02	2.59E-01
Huntington's disease	8A01.10	Whole blood	3.53E-01	1.12E-02	7.98E-02
Idiopathic pulmonary fibrosis	CB03.4	Lung tissue	5.43E-04	6.69E-01	3.07E+00
Immunodeficiency	4A00-4A20	Peripheral blood	5.58E-01	3.22E-02	3.54E-01
Influenza	1.00E+30	Whole blood	4.82E-01	-6.91E-02	-1.16E-01
Interstitial cystitis	GC00.3	Bladder tissue	2.53E-02	1.48E-01	2.36E+00
Intracranial aneurysm	8B01.0	Intracranial artery	3.22E-03	2.94E-01	2.03E+00
Irritable bowel syndrome	DD91.0	Rectal colon tissue	2.58E-02	7.81E-02	2.10E-01
Ischemic stroke	8B11	Peripheral blood	7.95E-01	5.88E-02	3.84E-01
Juvenile idiopathic arthritis	FA24	Peripheral blood	5.18E-01	1.43E-02	3.46E-02
Lateral sclerosis	8B60.4	Cervical spinal cord	5.23E-01	-1.22E-03	-1.90E-03
Lateral sclerosis	8B60.4	Skin	1.12E-02	3.60E-01	1.96E+00
Liver cancer	2C12.0	Liver tissue	1.96E-01	-8.57E-02	-4.40E-01
Liver failure	DB99.7-DB99.8	Liver tissue	2.24E-01	1.53E-01	8.07E-01
Lung cancer	2C25	Lung tissue	2.83E-02	-4.99E-02	-1.74E-01
Lupus erythematosus	4A40	Whole blood	6.91E-01	8.17E-03	2.69E-02
Major depressive disorder	6A70-6A7Z	Whole blood	8.51E-01	-3.79E-02	-1.07E-01
Major depressive disorder	6A70-6A7Z	Hippocampus	7.89E-01	1.13E-02	4.66E-02
Melanoma	2C30	Skin	4.75E-01	2.22E-01	3.07E-01
Multiple myeloma	2A83.1	Bone marrow	3.27E-06	-4.71E-01	-4.49E+00
Multiple myeloma	2A83.1	Peripheral blood	1.44E-01	8.83E-02	2.67E-01
Multiple sclerosis	8A40	Plasmacytoid dendritic cells	1.40E-03	3.39E-01	3.70E+00
Myelodysplastic syndrome	2A36-2A3Z	Bone marrow	6.11E-01	3.26E-02	1.28E-01
Myelofibrosis	2A20.2	Whole blood	9.26E-02	2.31E-02	1.76E-01
Myocardial infarction	BA41-BA50	Peripheral blood	2.94E-01	1.12E-01	1.60E-01
Myopathy	8C70.6	Muscle tissue	4.16E-01	-9.11E-02	-5.56E-01
Neonatal sepsis	KA60	Whole blood	3.43E-01	-2.82E-02	-1.50E-01
Neuroectodermal tumour	2A00.11	Brain stem tissue	5.05E-03	-3.77E-01	-1.14E+00
Non-alcoholic fatty liver disease	DB92	Liver tissue	9.34E-01	6.26E-03	5.10E-02
Obesity related type 2 diabetes	5A11	Omental adipose tissue	7.93E-01	7.16E-03	8.17E-02
Olive pollen allergy	CA08.00	Peripheral blood	8.18E-01	2.42E-01	1.94E-01
Oral cancer	2B6E	Oral tissue	9.82E-01	-1.37E-01	-4.13E-01
Osteoarthritis	FA00-FA0Z	Synovial tissue	9.15E-01	-1.37E-02	-4.80E-02
Osteoporosis	FB83.1	Bone marrow	4.42E-01	-1.00E-01	-2.01E-01
Ovarian cancer	2C73	Ovarian tissue	1.00E-01	-3.40E-01	-4.11E-01
Pancreatic cancer	2C10	Pancreas	2.46E-01	-2.62E-01	-5.12E-01
Parkinson's disease	8A00.0	Substantia nigra tissue	3.16E-02	-6.53E-01	-1.43E+00
Pediatric respiratory syncytial virus infection	CA40.11	Peripheral blood	2.04E-01	-7.96E-02	-5.70E-01
Pituitary cancer	2D12	Pituitary tissue	1.73E-01	-2.49E-01	-6.96E-01
Pituitary gonadotrope tumour	2D12	Pituitary tissue	1.35E-01	2.98E-01	7.06E-01
Polycystic ovary syndrome	5A80.1	Vastus lateralis muscle	8.42E-01	-3.63E-03	-2.50E-02
Polycythemia vera	2A20.4	Whole blood	5.68E-04	1.08E-01	8.17E-01
Pompe disease	5C51.3	Biceps muscle	2.67E-02	-1.64E-01	-8.47E-01
Preterm birth	KA21.4Z	Myometrium	9.49E-02	-1.27E-01	-7.64E-01
Prostate cancer	2C82	Prostate	6.47E-04	-5.45E-01	-1.33E+00
Psoriasis	EA90	Skin	2.33E-03	-1.31E-01	-4.51E-01
Rectal cancer	2B92	Rectal colon tissue	1.63E-04	2.04E-01	2.04E+00
Renal cancer	2C90-2C91	Kidney	1.68E-03	-5.54E-01	-1.46E+00
Retinoblastoma	2D02.2	Uvea	4.21E-06	-1.34E+00	-4.91E+00
Rheumatoid arthritis	FA20	Synovial tissue	6.51E-01	4.55E-02	1.99E-01
Rhinovirus infection	CA42.1	Nasal epithelium tissue	5.61E-01	3.14E-02	7.08E-02
Schizophrenia	6A20	Prefrontal cortex	2.74E-02	-2.72E-01	-2.67E-01
Schizophrenia	6A20	Superior temporal cortex	1.38E-01	-2.45E-01	-6.74E-01
Scleroderma	4A42.Z	Whole blood	4.69E-04	1.94E-01	1.90E+00
Seizure	8A60-8A6Z	Whole blood	7.24E-01	-4.57E-02	-3.52E-01
Sensitive skin	EK0Z	Skin	7.22E-01	-1.01E-01	-4.63E-01
Sepsis with septic shock	1G41	Whole blood	4.08E-03	-7.05E-02	-3.34E-01
Shwachman-Diamond syndrome	3A70.0	Bone marrow	9.88E-02	2.24E-01	1.30E+00
Sickle cell disease	3A51.0-3A51.3	Peripheral blood	3.32E-01	-1.67E-02	-1.04E-01
Simpson golabi behmel syndrome	LD2C	Adipose tissue	8.68E-01	-2.48E-02	-1.97E-01
Sjogren's syndrome	4A43.2	Salivary gland tissue	4.52E-01	-3.02E-01	-9.79E-01
Skin cancer	2C30-2C3Z	Skin	2.67E-12	1.79E-01	5.81E-01
Thrombocythemia	3B63	Whole blood	3.81E-03	1.01E-01	8.28E-01
Thrombocytopenia	3B64	Whole blood	7.91E-01	-4.55E-02	-1.12E-01
Thyroid cancer	2D10	Thyroid	1.69E-04	2.28E-02	1.22E-01
Tibial muscular dystrophy	8C75	Muscle tissue	3.76E-01	2.20E-02	1.26E-01
Tuberous sclerosis complex	LD2D.2	Perituberal tissue	4.56E-03	-6.83E-01	-2.52E+00
Type 2 diabetes	5A11	Liver tissue	8.70E-01	-1.79E-02	-8.20E-02
Ureter cancer	2C92	Urothelium	6.20E-01	9.59E-02	2.97E-01
Uterine cancer	2C78	Endometrium tissue	2.55E-01	6.35E-02	1.95E-01
Vitiligo	ED63.0	Skin	1.71E-01	8.76E-02	5.52E-01