Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DE3Z1RA)

DME Name	Pyridoxamine-phosphate oxidase (PNPO) DME Info
Gene Name	PNPO

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Pyridoxamine	DMVDCGZ	Diabetic kidney disease	GB61.Z	Phase 3	[1]
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1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Pyridoxine-5'-Phosphate	DMFUNL1	Discovery agent	N.A.	Investigative	[2]
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Molecule Interaction Atlas

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References

1	An LC-MS/MS-based method for the quantification of pyridox(am)ine 5'-phosphate oxidase activity in dried blood spots from patients with epilepsy. Anal Chem. 2017 Sep 5;89(17):8892-8900.
2	Pyridoxine 5'-phosphate oxidase is a novel therapeutic target and regulated by the TGF-beta signalling pathway in epithelial ovarian cancer. Cell Death Dis. 2017 Dec 13;8(12):3214.