Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DEAWHS8)

DME Name	Aldehyde oxidase (AOX1) DME Info
Gene Name	AOX1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Preclinical Drug(s)

Download the Complete Related Drug List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Zaleplon	DMGFWSM	Insomnia	7A00-7A0Z	Approved	[1]
Ziprasidone	DMM58JY	Bipolar disorder	6A60	Approved	[]
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2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
XL147	DMML7BE	Solid tumour/cancer	2A00-2F9Z	Phase 2	[1]
SGX523	DM3RSMF	Solid tumour/cancer	2A00-2F9Z	Phase 1	[2]
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1 Preclinical Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
VUFB-11502	DM7WFR0	N. A.	N. A.	Preclinical	[3]
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Molecule Interaction Atlas

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References

1	Characterization of aldehyde oxidase enzyme activity in cryopreserved human hepatocytes. Drug Metab Dispos. 2012 Feb;40(2):267-75.
2	Species-specific metabolism of SGX523 by aldehyde oxidase and the toxicological implications. Drug Metab Dispos. 2010 Aug;38(8):1277-85.
3	The critical role of oxidative stress in the toxicity and metabolism of quinoxaline 1,4-di-N-oxides in vitro and in vivo. Drug Metab Rev. 2016 May;48(2):159-82.