Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DEOCWU3)

• DME Name: Alcohol dehydrogenase class-II (ADH4) DME Info
• UniProt ID: ADH4_HUMAN
• Gene Name: ADH4

Molecule-Related Drug & Molecule List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[1]

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Androsterone	DMITJAK	N. A.	N. A.	Phase 3	[2]

7 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetaldehyde	DMJFKG4	Discovery agent	N.A.	Investigative	[1]
BRN-2330710	DM87VP6	Discovery agent	N.A.	Investigative	[1]
Hydroxymethylpyrene	DMPGAR2	Discovery agent	N.A.	Investigative	[1]
Octanal	DMTN0OK	Discovery agent	N.A.	Investigative	[1]
Octanol	DMBGHPE	Discovery agent	N.A.	Investigative	[1]
Pyrene-1-aldehyde	DMEF6IP	Discovery agent	N.A.	Investigative	[1]
Pyrenemethanol	DMGJ0RM	Discovery agent	N.A.	Investigative	[1]

References

• [1] Oxidation of alcohols and reduction of aldehydes derived from methyl- and dimethylpyrenes by cDNA-expressed human alcohol dehydrogenases. Toxicology. 2008 Mar 12;245(1-2):65-75.
• [2] 13-cis-retinoic acid competitively inhibits 3 alpha-hydroxysteroid oxidation by retinol dehydrogenase RoDH-4: a mechanism for its anti-androgenic effects in sebaceous glands? Biochem Biophys Res Commun. 2003 Mar 28;303(1):273-8.