Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DEOY5ZM)

DME Name	Aldo-keto reductase 1C2 (AKR1C2) DME Info
UniProt ID	AK1C2_HUMAN
Gene Name	AKR1C2

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fenofibric acid	DMGO2MC	Cardiovascular disease	BA00-BE2Z	Approved	[1]
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1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Trastuzumab Emtansine	DMU1LXS	HER2-positive breast cancer	2C60-2C65	Phase 2	[2]
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1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BRN-3548355	DM4KXT0	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	In vitro metabolism of fenofibric acid by carbonyl reducing enzymes. Chem Biol Interact. 2016 Oct 25;258:153-8.
2	The role of carbonyl reducing enzymes in oxcarbazepine in vitro metabolism in man. Chem Biol Interact. 2014 Sep 5;220:241-7.
3	Characterization of enzymes participating in carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human placenta. Chem Biol Interact. 2001 Jan 30;130-132(1-3):737-48.