Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DEZDRQO)

DME Name	Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) DME Info
Gene Name	HSD11B1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cortisone Acetate	DMG8K57	Acne vulgaris	ED80	Approved	[1]
Nabumetone	DMAT2XH	Osteoarthritis	FA00-FA05	Approved	[2]
------------------------------------------------------------------------------------

1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dehydrocorticosterone	DM48KMB	N. A.	N. A.	Investigative	[1]
------------------------------------------------------------------------------------

Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Comparative enzymology of 11beta-hydroxysteroid dehydrogenase type 1 from six species. J Mol Endocrinol. 2005 Aug;35(1):89-101.
2	Reductive metabolism of nabumetone by human liver microsomal and cytosolic fractions: exploratory prediction using inhibitors and substrates as marker probes. Eur J Drug Metab Pharmacokinet. 2015 Jun;40(2):127-35.