Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTP (ID: DTKVEXO)

DTP Name	ATP-binding cassette sub-family B member 5 (ABCB5) DTP Info
Gene Name	ABCB5

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

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3 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Brigatinib	DM7W94S	Anaplastic large cell lymphoma	2A90.A	Approved	[1]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[2]
Fostamatinib	DM6AUHV	Immune thrombocytopenic purpura	3B64.13	Approved	[3]
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Molecule Interaction Atlas

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References

1	NDA/BLA Multidisciplinary Review and Evaluation of ALUNBRIG (brigatinib) From FDA.
2	ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma. Cancer Res. 2005 May 15;65(10):4320-33.
3	DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. (ID: DB12010)