Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTP (ID: DTP8L4F)

DTP Name	High affinity copper uptake protein 1 (SLC31A1) DTP Info
Gene Name	CTR1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Download the Complete Related Drug List

4 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Carboplatin	DMG281S	Adenocarcinoma	2D40	Approved	[1]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[1]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[2]
Oxaliplatin	DMQNWRD	Adenocarcinoma	2D40	Approved	[3]
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Molecule Interaction Atlas

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References

1	Overcoming platinum drug resistance with copper-lowering agents. Anticancer Res. 2013 Oct;33(10):4157-61.
2	Role of the copper transporter, CTR1, in platinum-induced ototoxicity. J Neurosci. 2010 Jul 14;30(28):9500-9.
3	Copper transporters regulate the cellular pharmacology and sensitivity to Pt drugs. Crit Rev Oncol Hematol. 2005 Jan;53(1):13-23.