Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTP (ID: DTPS120)

• DTP Name: Multidrug resistance-associated protein 7 (ABCC10) DTP Info
• Gene Name: MRP7

Molecule-Related Drug & Molecule List

4 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Docetaxel	DMDI269	Advanced cancer	2A00-2F9Z	Approved	[1]
Paclitaxel	DMLB81S	Breast carcinoma		Approved	[1]
Tamoxifen	DMLB0EZ	Breast cancer	2C60-2C65	Approved	[1]
Tenofovir	DM1IS6U	Chronic hepatitis B virus infection		Approved	[2]

References

• [1] Modulation of the ATPase and transport activities of broad-acting multidrug resistance factor ABCC10 (MRP7). Cancer Res. 2012 Dec 15;72(24):6457-67.
• [2] Genetic variants of ABCC10, a novel tenofovir transporter, are associated with kidney tubular dysfunction. J Infect Dis. 2011 Jul 1;204(1):145-53.