Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTP (ID: DTT7VPB)

DTP Name	Vesicular amine transporter 2 (SLC18A2) DTP Info
UniProt ID	VMAT2_HUMAN
Gene Name	VMAT2

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Investigative Drug(s)

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4 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dopamine	DMPGUCF	Parkinson disease	8A00.0	Approved	[1]
Ergotidine	DM78IME	Respiratory allergy	4A80	Approved	[2]
Methamphetamine	DMPM4SK	Attention deficit hyperactivity disorder	6A05.Z	Approved	[3]
Norepinephrine	DMOUC09	Sepsis	1G40-1G41	Approved	[1]
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1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Serotonin	DMOFCRY	Discovery agent	N.A.	Investigative	[1]
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Molecule Interaction Atlas

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References

1	SLC18: Vesicular neurotransmitter transporters for monoamines and acetylcholine. Mol Aspects Med. 2013 Apr-Jun;34(2-3):360-72.
2	The vesicular monoamine transporter 2: an underexplored pharmacological target. Neurochem Int. 2014 Jul;73:89-97.
3	Synthesis and Discovery of Arylpiperidinylquinazolines: New Inhibitors of the Vesicular Monoamine Transporter. J Med Chem. 2018 Oct 25;61(20):9121-9131.