Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT09NOX)

• DTT Name: Plasmodium Dihydroorotase (Malaria dho) DTT Info
• UniProt ID: A9CSR1_PLAFA
• Gene Name: Malaria dho

Molecule-Related Drug & Molecule List

8 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
5-bromo orotate	DM0HCG6	Discovery agent	N.A.	Investigative	[1]
5-Fluoro orotate	DMLSC10	Discovery agent	N.A.	Investigative	[1]
5-iodo orotate	DMDKFIO	Discovery agent	N.A.	Investigative	[1]
5-methyl orotate	DMYNFIP	Discovery agent	N.A.	Investigative	[1]
Dihydroorotate	DM76BGZ	Discovery agent	N.A.	Investigative	[2]
Lysine Nz-Carboxylic Acid	DMW1YK3	Discovery agent	N.A.	Investigative	[2]
N-Carbamoyl-L-Aspartate	DMJ13TR	Discovery agent	N.A.	Investigative	[2]
Orotate	DMMB29S	Discovery agent	N.A.	Investigative	[1]

References

• [1] Antimalarial activity of orotate analogs that inhibit dihydroorotase and dihydroorotate dehydrogenase. Biochem Pharmacol. 1992 Mar 17;43(6):1295-301.
• [2] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.