Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT0F5HE)

DTT Name	HUMAN janus kinase 2 (JAK-2) DTT Info
Gene Name	JAK2

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Download the Complete Related Drug List

2 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fedratinib	DM4ZBK6	Myelofibrosis	2A20.2	Approved	[1]
Ruxolitinib	DM7Q98D	Essential thrombocythemia	3B63.1Z	Approved	[2]
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Molecule Interaction Atlas

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References

1	TH17 responses in cytokine storm of COVID-19: An emerging target of JAK2 inhibitor Fedratinib. J Microbiol Immunol Infect. 2020 Mar 11. pii: S1684-1182(20)30065-7.
2	The Use of Anti-Inflammatory Drugs in the Treatment of People With Severe Coronavirus Disease 2019 (COVID-19): The Perspectives of Clinical Immunologists From China. Clin Immunol. 2020 May;214:108393.