Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT0J32Z)

DTT Name	Smad7 messenger RNA (Smad7 mRNA) DTT Info
Gene Name	SMAD7

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GED-0301	DMTUV7L	Crohn disease	DD70	Phase 3	[1]
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4 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 28465	DMQ5JNT	Discovery agent	N.A.	Investigative	[2]
ISIS 28466	DMH96UP	Discovery agent	N.A.	Investigative	[2]
ISIS 28472	DMA4U2P	Discovery agent	N.A.	Investigative	[2]
ISIS 28477	DMMOV9U	Discovery agent	N.A.	Investigative	[2]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	A phase 1 open-label trial shows that smad7 antisense oligonucleotide (GED0301) does not increase the risk of small bowel strictures in Crohn's disease. Aliment Pharmacol Ther. 2012 Nov;36(9):850-7.
2	US patent application no. 6,159,697, Antisense modulation of Smad7 expression.