Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT1KPBZ)

• DTT Name: Glucose-6-phosphate translocase (SLC37A4) DTT Info
• Gene Name: SLC37A4

Molecule-Related Drug & Molecule List

8 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Chlorogenic acid	DM2Y3P4	Discovery agent	N.A.	Investigative	[1]
Kodaistatin A	DMAJKRX	Discovery agent	N.A.	Investigative	[2]
Kodaistatin C	DM72WQ3	Discovery agent	N.A.	Investigative	[2]
Mumbaistatin	DM6SYMH	Discovery agent	N.A.	Investigative	[3]
S 0957	DM9HA8G	Discovery agent	N.A.	Investigative	[4]
S 1743	DMA5GOX	Discovery agent	N.A.	Investigative	[4]
S 3025	DMZN0RW	Discovery agent	N.A.	Investigative	[5]
S-4048	DME5HIR	Discovery agent	N.A.	Investigative	[6]

References

• [1] Chlorogenic acid and synthetic chlorogenic acid derivatives: novel inhibitors of hepatic glucose-6-phosphate translocase. J Med Chem. 1997 Jan 17;40(2):137-45.
• [2] Kodaistatins, novel inhibitors of glucose-6-phosphate translocase T1 from Aspergillus terreus thom DSM 11247. Isolation and structural elucidation. J Antibiot (Tokyo). 2000 Jul;53(7):677-86.
• [3] Studies toward the total synthesis of mumbaistatin, a highly potent glucose-6-phosphate translocase inhibitor. Synthesis of a mumbaistatin analogue. J Org Chem. 2002 Dec 27;67(26):9248-56.
• [4] Identification of protein components of the microsomal glucose 6-phosphate transporter by photoaffinity labelling. Biochem J. 1999 May 1;339 ( Pt 3):629-38.
• [5] Prolonged blood glucose reduction in mrp-2 deficient rats (GY/TR(-)) by the glucose-6-phosphate translocase inhibitor S 3025. Biochim Biophys Acta. 2002 Jan 15;1569(1-3):105-10.
• [6] Glucose release from GLUT2-null hepatocytes: characterization of a major and a minor pathway. Am J Physiol Endocrinol Metab. 2002 Apr;282(4):E794-801.