Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT1UCIJ)

• DTT Name: C-X-C chemokine receptor type 3 (CXCR3) DTT Info
• Gene Name: CXCR3

Molecule-Related Drug & Molecule List

1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
T487	DMZTL7H	Psoriatic disorder	EA90	Discontinued in Phase 2	[1]

2 Preclinical Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
dioscin	DM5H2W9	Hepatic fibrosis	DB93.0	Preclinical	[2]
JT07	DMHBWOP	Solid tumour/cancer	2A00-2F9Z	Preclinical	[3]

4 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
hypoglaucin A	DMJKIUX	Discovery agent	N.A.	Investigative	[2]
kallstroemin D	DM7YAE0	Discovery agent	N.A.	Investigative	[2]
NBI-74330	DMURC6X	Discovery agent	N.A.	Investigative	[1]
Sch-900875	DM346KA	Inflammation	1A00-CA43.1	Investigative	[4]

References

• [1] Pharmacological characterization of CXC chemokine receptor 3 ligands and a small molecule antagonist. J Pharmacol Exp Ther. 2005 Jun;313(3):1263-71.
• [2] Discovery of structurally diverse natural product antagonists of chemokine receptor CXCR3. Mol Divers. 2005;9(1-3):123-9.
• [3] Clinical pipeline report, company report or official report of Jyant Technologies.
• [4] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 70).