Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT27K59)

• DTT Name: Platelet activating factor (PAF) DTT Info
• Gene Name: PAF

Molecule-Related Drug & Molecule List

1 Preclinical Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Indol-3-carbinol	DMXJO20	Fungal infection	1F29-1F2F	Preclinical	[1]

3 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
F-0401	DMR1X2U	N. A.	N. A.	Terminated	[2]
SRI 63-441	DMMPSY2	N. A.	N. A.	Terminated	[3]
UR-12670	DM7F94W	N. A.	N. A.	Terminated	[4]

1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SCH 44643	DMNLD6W	Discovery agent	N.A.	Investigative	[5]

References

• [1] Pinusolide from the leaves of Biota orientalis as potent platelet activating factor antagonist. Planta Med. 1999 Feb;65(1):39-42.
• [2] Protective effects of a novel calcium antagonist with platelet-activating factor-antagonistic action, F-0401, against ischemic brain damage. Arch Int Pharmacodyn Ther. 1994 May-Jun;327(3):266-78.
• [3] Pharmacologic modulation of experimental postischemic hepatic function. Ann Surg. 1989 Feb;209(2):200-10.
• [4] Long-term protective effect of UR-12670 after warm renal ischemia in uninephrectomized rats. Kidney Int. 1999 Nov;56(5):1798-808.
• [5] Determination of plasma concentrations of SCH 44643 by a GC method and correlation of plasma concentration and anti-PAF activity in cynomolgus monkeys. J Pharm Biomed Anal. 1996 Dec;15(3):343-7.