Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT2L4TV)

• DTT Name: SERPINA1 messenger RNA (SERPINA1 mRNA) DTT Info
• Gene Name: SERPINA1

Molecule-Related Drug & Molecule List

3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fazirsiran	DM772MW	Alpha-1 antitrypsin deficiency	5C5A	Phase 3	[1]
ARO-AAT	DM2UP6Z	Alopecia	ED70	Phase 2	[2]
Belcesiran	DMLMIGI	Alpha-1 antitrypsin deficiency	5C5A	Phase 2	[3]

References

• [1] Fazirsiran for Liver Disease Associated with Alpha(1)-Antitrypsin Deficiency. N Engl J Med. 2022 Aug 11;387(6):514-524.
• [2] Clinical pipeline report, company report or official report of Arrowhead Pharmaceuticals.
• [3] Clinical pipeline report, company report or official report of Dicerna Pharmaceuticals