Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT4EN8X)

DTT Name	Caterpiller protein 1.1 (NLRP3) DTT Info
Gene Name	NLRP3

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dapansutrile	DM7IH48	Acute gout flare	FA25.0	Phase 2	[1]
BMS-986299	DMTMUWJ	Solid tumour/cancer	2A00-2F9Z	Phase 1	[2]
Selnoflast	DM4NKNK	Inflammation	1A00-CA43.1	Phase 1	[3]
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1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
MCC950	DM6J2UZ	Discovery agent	N.A.	Investigative	[4]
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Molecule Interaction Atlas

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References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	National Cancer Institute Drug Dictionary (drug name BMS-986299).
3	Clinical pipeline report, company report or official report of Roche
4	A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nat Med. 2015 Mar;21(3):248-55.