Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT51DEV)

DTT Name	Interleukin 1 receptor type 2 (IL1R2) DTT Info
Gene Name	IL1R2

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Discontinued Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GSK-1827771	DMA41JD	Rheumatoid arthritis	FA20	Phase 1	[1]
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3 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AMG 108	DMMUS8X	Rheumatoid arthritis	FA20	Discontinued in Phase 2	[2]
FR-133605	DMXWL0N	Arthritis	FA20	Terminated	[3]
MRL-953	DM4A92X	Immune System disease	4A01-4B41	Terminated	[4]
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Molecule Interaction Atlas

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References

1	WO patent application no. 2013,0077,63, Modulators of the nlrp3 inflammasome il-1ss pathway for the prevention and treatment of acne.
2	Clinical pipeline report, company report or official report of Amgen (2009).
3	Effect of FR133605, a novel cytokine suppressive agent, on bone and cartilage destruction in adjuvant arthritic rats. J Rheumatol. 1996 Oct;23(10):1778-83.
4	SDZ MRL 953, a lipid A analog as selective cytokine inducer. Prog Clin Biol Res. 1995;392:549-65.