Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT5FOMZ)

DTT Name	Thymidylate synthase (TYMS) DTT Info
Gene Name	TYMS

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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2 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Plevitrexed (R)-isomer	DMTL39C	Gastric adenocarcinoma	2B72	Phase 2	[1]
NUC-3373	DMQ0F5P	Solid tumour/cancer	2A00-2F9Z	Phase 1	[2]
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1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ICI-198583	DMW4L3K	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	Differential effect of 1,10-phenanthroline on mammalian, yeast, and parasite glycosylphosphatidylinositol anchor synthesis. Biochem Biophys Res Commun. 2001 Nov 16;288(5):1112-8.
2	Clinical pipeline report, company report or official report of NuCana.
3	The biochemical pharmacology of the thymidylate synthase inhibitor, 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583). Biochem Pharmacol. 1991 Oct 24;42(10):1885-95.