Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT5OEKU)

• DTT Name: Voltage-gated potassium channel Kv2.1 (KCNB1) DTT Info
• Gene Name: KCNB1

Molecule-Related Drug & Molecule List

4 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
3-bicyclo[2.2.1]hept-2-yl-benzene-1,2-diol	DMZ8WMA	Discovery agent	N.A.	Investigative	[1]
DABCO-C16	DMN3GTF	Discovery agent	N.A.	Investigative	[2]
RY796	DMW4850	Discovery agent	N.A.	Investigative	[3]
[14C]TEA	DM6SFYH	Discovery agent	N.A.	Investigative	[4]

References

• [1] Novel neuroprotective K+ channel inhibitor identified by high-throughput screening in yeast. Mol Pharmacol. 2004 Jan;65(1):214-9.
• [2] 1,4-Diazabicyclo[2.2.2]octane derivatives: a novel class of voltage-gated potassium channel blockers. Mol Pharmacol. 2006 Mar;69(3):718-26.
• [3] Identification of novel and selective Kv2 channel inhibitors. Mol Pharmacol. 2011 Dec;80(6):959-64.
• [4] Modulation of Kv2.1 channel gating and TEA sensitivity by distinct domains of SNAP-25. Biochem J. 2006 Jun 1;396(2):363-9.