Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT5TQ2W)

DTT Name	Granulocyte colony-stimulating factor (CSF3) DTT Info
Gene Name	CSF3

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

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3 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Efbemalenograstim	DMDNJ18	Neutropenia	4B00.0	Approved	[1]
Eflapegrastim	DMACVEI	Neutropenia	4B00.0	Approved	[2]
Interleukin-3	DM1Y69Q	Aplastic anemia	3A70	Approved	[3]
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4 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Neugranin	DMLRKJX	Neutropenia	4B00.0	Preregistration	[4]
DA-3031	DM6S4R2	Neutropenia	4B00.0	Phase 3	[5]
LA-EP2006	DMI3YLK	Neutropenia	4B00.0	Phase 3	[6]
MK-4214	DMA25NO	Neutropenia	4B00.0	Phase 3	[7]
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Molecule Interaction Atlas

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References

1	Clinical pipeline report, company report or official report of Generon (Shanghai) Corporation Ltd.
2	Company report (Sppirx)
3	Interleukin 3: from colony-stimulating factor to pluripotent immunoregulatory cytokine. Int J Immunopharmacol. 1992 Apr;14(3):421-30.
4	Development and Characterization of a Novel Fusion Protein of a Mutated Granulocyte Colony-Stimulating Factor and Human Serum Albumin in Pichia pastoris. PLoS One. 2014; 9(12): e115840.
5	A randomized, multi-center, open-label, phase II study of once-per-cycle DA-3031, a biosimilar pegylated G-CSF, compared with daily filgrastim in patients receiving TAC chemotherapy for early-stage breast cancer.Invest New Drugs.2013 Oct;31(5):1300-6.
6	National Cancer Institute Drug Dictionary (drug id 724518).
7	DOI: 10.1038/nbt0710-636a