Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT5WLRX)

DTT Name	TRAIL receptor 1 (TRAIL-R1) DTT Info
Gene Name	TNFRSF10A

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Discontinued Drug(s)

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Mapatumumab	DMGQ175	Non-small-cell lung cancer	2C25.Y	Phase 2	[1]
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1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
RhApo2L/TRAIL	DMIAZJ9	Solid tumour/cancer	2A00-2F9Z	Discontinued in Phase 1/2	[2]
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1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
DR-5/DR-4 cross reactive mabs	DMX2TZD	Solid tumour/cancer	2A00-2F9Z	Investigative	[3]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	National Cancer Institute Drug Dictionary (drug id 486626).
2	Clinical pipeline report, company report or official report of Amgen (2009).
3	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1879).