Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT9R6BE)

• DTT Name: Calcium-activated potassium channel KCa2.1 (KCNN1) DTT Info
• Gene Name: KCNN1

Molecule-Related Drug & Molecule List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
dequalinium	DMXM19W	Myelopathy	8B42	Clinical trial	[1]

5 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
apamin	DMYNBK5	Discovery agent	N.A.	Investigative	[1]
EBIO	DMPKI0N	Discovery agent	N.A.	Investigative	[2]
UCL1684	DMZNJFU	Discovery agent	N.A.	Investigative	[2]
UCL1848	DM2CN0A	Discovery agent	N.A.	Investigative	[3]
[14C]TEA	DM6SFYH	Discovery agent	N.A.	Investigative	[2]

References

• [1] Pharmacological characterization of small-conductance Ca(2+)-activated K(+) channels stably expressed in HEK 293 cells. Br J Pharmacol. 2000 Mar;129(5):991-9.
• [2] Small conductance calcium-activated potassium channels: from structure to function. Prog Neurobiol. 2010 Jul;91(3):242-55.
• [3] The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines. Br J Pharmacol. 2000 Feb;129(4):627-30.