General Information of DTT (ID: TT9XBVO)

DTT Name Mucolipin-1 (TRPML1) DTT Info
Gene Name MCOLN1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Preclinical Drug(s)
Investigative Drug(s)
1 Preclinical Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
MK6-83 DMI3E0Y Discovery agent N.A. Preclinical [1]
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1 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
phosphatidyl (3,5) inositol biphosphate DMMHQYB Discovery agent N.A. Investigative [2]
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Molecule Interaction Atlas

References

1 ML-SA1, a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity. Antiviral Res. 2020 Oct;182:104922.
2 PI(3,5)P(2) controls membrane trafficking by direct activation of mucolipin Ca(2+) release channels in the endolysosome. Nat Commun. 2010 Jul 13;1:38.