Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTAD1O8)

DTT Name	V-erbA-related protein 1 (NR1D1) DTT Info
Gene Name	NR1D1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Preclinical Drug(s)

Download the Complete Related Drug List

4 Preclinical Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GSK4112	DM1S5UO	Inflammation	1A00-CA43.1	Preclinical	[1]
SR8278	DMSK5N3	Myocardial disease	BC43.20	Preclinical	[1]
SR9009	DM8SKU1	Solid tumour/cancer	2A00-2F9Z	Preclinical	[2]
SR9011	DMZ9BO8	Solid tumour/cancer	2A00-2F9Z	Preclinical	[2]
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Molecule Interaction Atlas

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References

1	Identification of SR8278, a synthetic antagonist of the nuclear heme receptor REV-ERB. ACS Chem Biol. 2011 Feb 18;6(2):131-4.
2	Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence. Nature. 2018 Jan 18;553(7688):351-355.