General Information of DTT (ID: TTC9IZL)

DTT Name Inositol 1,4,5-trisphosphate receptor (ITPR) DTT Info
Gene Name ITPR1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Approved Drug(s)
Investigative Drug(s)
1 Approved Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitroprusside DMLUA2J Hypertension BA00-BA04 Approved [1]
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3 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
5'-Deoxy-5'-phenyladenophostin A DMU4MCK Discovery agent N.A. Investigative [2]
ADENOPHOSTIN A DMV39AW Discovery agent N.A. Investigative [2]
D-myo-inositol 1,4,5-trisphosphate DMNUKIX Discovery agent N.A. Investigative [3]
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Molecule Interaction Atlas

References

1 Prostacyclin and sodium nitroprusside inhibit the activity of the platelet inositol 1,4,5-trisphosphate receptor and promote its phosphorylation. J Biol Chem. 1996 Mar 8;271(10):5545-51.
2 Synthesis of adenophostin A analogues conjugating an aromatic group at the 5'-position as potent IP3 receptor ligands. J Med Chem. 2006 Sep 21;49(19):5750-8.
3 DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.