Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTDO1MV)

DTT Name	T-cell activation antigen CD27 (CD27) DTT Info
Gene Name	CD27

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

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3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Varlilumab	DMQSC5O	Colorectal cancer	2B91.Z	Phase 2	[1]
CDX-1127	DMPVUGE	leukaemia	2A60-2B33	Phase 1	[2]
CDX-527	DMVDIWO	Solid tumour/cancer	2A00-2F9Z	Phase 1	[3]
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Molecule Interaction Atlas

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References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	Clinical pipeline report, company report or official report of Celldex Therapeutics.
3	Development of CDX-527: a bispecific antibody combining PD-1 blockade and CD27 costimulation for cancer immunotherapy. Cancer Immunol Immunother. 2020 Oct;69(10):2125-2137.