General Information of DTT (ID: TTEOSZT)

DTT Name Melanocortin receptor (MCR) DTT Info
Gene Name MCR

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
1 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
ASP-3291 DMBADQV Ulcerative colitis DD71 Phase 2 [1]
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39 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ac-His-DNal(2)-Arg-Trp-NH2 DMUEBRN Discovery agent N.A. Investigative [2]
Ac-His-DPhe(3,4-diCl)-Arg-Trp-NH2 DMR31Z9 Discovery agent N.A. Investigative [2]
Ac-His-DPhe(pBr)-Arg-Trp-NH2 DMXU5ZP Discovery agent N.A. Investigative [2]
Ac-His-DPhe(pCF3)-Arg-Trp-NH2 DMTA6I5 Discovery agent N.A. Investigative [2]
Ac-His-DPhe(pI)-Arg-Trp-NH2 DM3GSPX Discovery agent N.A. Investigative [2]
Ac-Nle-c[Asp-His-DNal(2')-Pro-Trp-Lys]-NH2 DMOVI7Y Discovery agent N.A. Investigative [3]
Ac-YRC(Me)*EHdFRWC(Me)NH2 DMWJ8UR Discovery agent N.A. Investigative [4]
Ac-YRMEHdFRWG-NH2 DMN2UKC Discovery agent N.A. Investigative [4]
Ac-YRMEHdFRWGSPPKD-NH2 DMDH5B3 Discovery agent N.A. Investigative [4]
Ac-YR[CEH(d-2alpha-Nal)RWC]-NH2 DMVQ4KG Discovery agent N.A. Investigative [4]
Ac-YR[CEH(pCl-dF)RWC]-NH2 DM25JXM Discovery agent N.A. Investigative [4]
Ac-YR[CEH(pF-dF)RWC]-NH2 DMXCF9T Discovery agent N.A. Investigative [4]
AEKKDEGPYRMEHFRWGSPPKD DMZ8SV3 Discovery agent N.A. Investigative [4]
C[CO-(CH2)2-CO-Nle-D-Nal(2)-Arg-Trp-Lys]-NH2 DMHARQX Discovery agent N.A. Investigative [5]
C[CO-(CH2)2-CO-Nle-D-Phe-Arg-Trp-Lys]-NH2 DMI3CSJ Discovery agent N.A. Investigative [5]
C[CO-(CH2)3-CO-Pro-D-Nal(2)-Arg-Trp-Lys]-NH2 DMYPHVC Discovery agent N.A. Investigative [5]
C[CO-(CH2)3-CO-Pro-D-Phe-Arg-Trp-Lys]-NH2 DM0VP79 Discovery agent N.A. Investigative [5]
C[CO-2,3-pyrazine-CO-D-Nal(2)-Arg-Trp-Lys]-NH2 DM1VCJP Discovery agent N.A. Investigative [5]
C[CO-o-C6H4-CO-Pro-D-Nal(2)-Arg-Trp-Lys]-NH2 DMD6OW4 Discovery agent N.A. Investigative [5]
C[Nle-Arg-D-Nal(2')-Arg-Trp-Glu]-NH2 DMX7IVO Discovery agent N.A. Investigative [6]
C[Nle-Arg-D-Phe-Arg-Trp-Glu]-NH2 DMUESCH Discovery agent N.A. Investigative [6]
C[Nle-Asp-D-Nal(2')-Arg-Trp-Glu]-NH2 DM8SXLR Discovery agent N.A. Investigative [6]
C[Nle-Gln-D-Nal(2')-Arg-Trp-Glu]-NH2 DMM19SJ Discovery agent N.A. Investigative [6]
C[Nle-Gln-D-Phe-Arg-Trp-Glu]-NH2 DMSGWZE Discovery agent N.A. Investigative [6]
C[Nle-Glu-D-Nal(2')-Arg-Trp-Glu]-NH2 DMHNCAG Discovery agent N.A. Investigative [6]
C[Nle-Glu-D-Phe-Arg-Trp-Glu]-NH2 DMVWOPG Discovery agent N.A. Investigative [6]
C[Nle-His-D-Nal(2')-Arg-Trp-Glu]-NH2 DM36HBK Discovery agent N.A. Investigative [6]
C[Nle-His-D-Phe-Arg-Trp-Glu]-NH2 DM5HRNM Discovery agent N.A. Investigative [6]
C[Nle-Nle-D-Nal(2')-Arg-Trp-Glu]-NH2 DM73ZMG Discovery agent N.A. Investigative [6]
C[Nle-Nle-D-Phe-Arg-Trp-Glu]-NH2 DMDPBVS Discovery agent N.A. Investigative [6]
C[Nle-Pro-D-Nal(2')-Arg-Trp-Glu]-NH2 DMPZ4VB Discovery agent N.A. Investigative [6]
C[Nle-Pro-D-Phe-Arg-Trp-Glu]-NH2 DMZWMV0 Discovery agent N.A. Investigative [6]
C[Nle-Val-D-Nal(2')-Arg-Trp-Glu]-NH2 DMSIGJW Discovery agent N.A. Investigative [6]
C[Nle-Val-D-Phe-Arg-Trp-Glu]-NH2 DM45ZLW Discovery agent N.A. Investigative [6]
GPYRMEHFRWGSPPKD-NH2 DMLRTPH Discovery agent N.A. Investigative [4]
MK-10 DMI7859 Discovery agent N.A. Investigative [7]
MK-11 DM4FG32 Discovery agent N.A. Investigative [7]
MT-II DMKT1DA Female sexual arousal dysfunction HA01.1 Investigative [3]
NDP-SYSMEHFRWGKPVG DMRV16G Discovery agent N.A. Investigative [4]
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⏷ Show the Full List of 39 Investigative Drug(s)
Molecule Interaction Atlas

References

1 Clinical pipeline report, company report or official report of Drais Pharmaceuticals.
2 Melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 modified at the para position of the benzyl side chain (DPhe): importance for mouse melanocortin-... J Med Chem. 2008 Sep 25;51(18):5585-93.
3 Substitution of arginine with proline and proline derivatives in melanocyte-stimulating hormones leads to selectivity for human melanocortin 4 rece... J Med Chem. 2009 Jun 25;52(12):3627-35.
4 Discovery of a beta-MSH-derived MC-4R selective agonist. J Med Chem. 2005 May 5;48(9):3095-8.
5 Structure-activity relationships of cyclic lactam analogues of alpha-melanocyte-stimulating hormone (alpha-MSH) targeting the human melanocortin-3 ... J Med Chem. 2008 Jan 24;51(2):187-95.
6 Development of cyclic gamma-MSH analogues with selective hMC3R agonist and hMC3R/hMC5R antagonist activities. J Med Chem. 2006 Mar 23;49(6):1946-52.
7 Novel cyclic templates of alpha-MSH give highly selective and potent antagonists/agonists for human melanocortin-3/4 receptors. J Med Chem. 2002 Jun 6;45(12):2644-50.