Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTFH2RS)

DTT Name	FK506-binding protein (FKBP) DTT Info
Gene Name	FKBP

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Discontinued Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ascrolimus	DMZF68E	Psoriasis vulgaris	EA90	Phase 2	[1]
FK-505	DMGROQP	Hyperuricaemia	5C55.Y	Phase 2	[2]
Timcodar dimesilate	DMDJLX7	Solid tumour/cancer	2A00-2F9Z	Phase 1/2	[3]
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1 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
T-506	DM7XGJY	Solid tumour/cancer	2A00-2F9Z	Discontinued in Phase 2	[4]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Mode of action of tacrolimus (FK506): molecular and cellular mechanisms. Ther Drug Monit. 1995 Dec;17(6):584-91.
2	Prevention of Cardiac Hypertrophy by Calcineurin Inhibition. Circulation Research. 1999; 84: 623-632.
3	Analysis of FK506, timcodar (VX-853) and FKBP51 and FKBP52 chaperones in control of glucocorticoid receptor activity and phosphorylation. Pharmacol Res Perspect. 2014 December; 2(6): e00076.
4	EP patent application no. 0831812, Methods and compositions for stimulating neurite growth.