Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTG68FB)

• DTT Name: Interleukine 12 (IL-12) DTT Info
• Gene Name: IL-12

Molecule-Related Drug & Molecule List

6 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ABP 654	DM0GXWT	Plaque psoriasis	EA90.0	Phase 3	[1]
Ad-RTS-hIL-12	DMCNTFW	Glioblastoma of brain	2A00.00	Phase 2	[2]
GEN-1	DMJN09S	Ovarian cancer	2C73	Phase 2	[3]
Tavokinogene telseplasmid	DMZX0VF	Melanoma	2C30	Phase 2	[4]
M9241	DMZUM67	Pancreatic cancer	2C10	Phase 1	[5]
MEDI1191	DMD9OVI	Solid tumour/cancer	2A00-2F9Z	Phase 1	[6]

1 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
YH010	DMA1T66	Aggressive cancer	2A00-2F9Z	Investigative	[7]

References

• [1] Clinical pipeline report, company report or official report of Amgen
• [2] Clinical pipeline report, company report or official report of Ziopharm Oncology.
• [3] Clinical pipeline report, company report or official report of Celsion.
• [4] Intratumoral delivery of tavokinogene telseplasmid yields systemic immune responses in metastatic melanoma patients. Ann Oncol. 2020 Apr;31(4):532-540.
• [5] Clinical pipeline report, company report or official report of EMD Serono.
• [6] Intratumoral IL12 mRNA Therapy Promotes TH1 Transformation of the Tumor Microenvironment. Clin Cancer Res. 2020 Dec 1;26(23):6284-6298.
• [7] Clinical pipeline report, company report or official report of Biocytogen