Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTGKIED)

• DTT Name: Fibroblast growth factor-2 (FGF2) DTT Info
• Gene Name: FGF2

Molecule-Related Drug & Molecule List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sucralfate	DMP9HBO	Acne vulgaris	ED80	Approved	[1]

4 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Squalamine	DM3PS2E	Solid tumour/cancer	2A00-2F9Z	Phase 3	[2]
Bemarituzumab	DMWNYIE	Gastric adenocarcinoma	2B72	Phase 2	[3]
DVC1-0101	DMUGBQK	Arteriosclerosis	BD40	Phase 2	[4]
FPA144	DM1EBRK	Bladder cancer	2C94	Phase 1	[5]

2 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
TGP-580	DMYN6G0	Neurodegenerative disorder	8A20-8A23	Discontinued in Phase 2	[6]
RG-8803	DMI0CYV	Diabetic retinopathy	9B71.0	Terminated	[7]

5 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid	DM4RD2S	Discovery agent	N.A.	Investigative	[8]
1,4-Dideoxy-O2-Sulfo-Glucuronic Acid	DM9KUQZ	Discovery agent	N.A.	Investigative	[8]
2-Sulfhydryl-Ethanol	DMJBO3D	Discovery agent	N.A.	Investigative	[8]
BIBF100	DMUWO6D	Multiple myeloma	2A83	Investigative	[9]
N,O6-Disulfo-Glucosamine	DMYCV7U	Discovery agent	N.A.	Investigative	[8]

References

• [1] Assessment of sucralfate coating by sequential scintigraphic imaging in radiation-induced esophageal lesions. Gastrointest Endosc. 1995 Feb;41(2):109-14.
• [2] Clinical pipeline report, company report or official report of Ohr Pharmaceutical.
• [3] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [4] DVC1-0101 to treat peripheral arterial disease: a Phase I/IIa open-label dose-escalation clinical trial. Mol Ther. 2013 Mar;21(3):707-14.
• [5] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [6] Expression of fibroblast growth factor-2 transcripts in the healing of acetic acid-induced gastric ulcers. APMIS. 1999 Aug;107(8):767-72.
• [7] US patent application no. 2010,0278,784, Methods and compositions for treating skin conditions.
• [8] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [9] Emerging therapies for multiple myeloma. Expert Opin Emerg Drugs. 2009 Mar;14(1):99-127.