Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTGY8IW)

• DTT Name: B2 bradykinin receptor (BDKRB2) DTT Info
• Gene Name: BDKRB2

Molecule-Related Drug & Molecule List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Icatibant	DMQPTOZ	Hereditary angioedema	4A00.14	Approved	[1]

5 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Anatibant	DMG7IEN	Traumatic brain injury	NA07.Z	Phase 2	[2]
DELTIBANT	DM5CB8U	Sepsis	1G40-1G41	Phase 2	[3]
DM199	DM0157T	Cerebral ischemia	8B11	Phase 2	[4]
Fasitibant chloride	DM563NC	Osteoarthritis	FA00-FA05	Phase 2	[5]
BRADYKININ	DM4R6UV	N. A.	N. A.	Phase 1	[6]

7 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Labradimil	DMSFL76	Brain cancer	2A00	Discontinued in Phase 2	[7]
NPC-567	DMAVZ1F	Rhinitis	FA20	Discontinued in Phase 2	[8]
CP-0597	DMS23JX	Asthma	CA23	Terminated	[9]
FR-172357	DMY1LRI	Inflammation	1A00-CA43.1	Terminated	[10]
FR-173657	DM37OS4	N. A.	N. A.	Terminated	[11]
JSM-10292	DMU5TGC	Pain	MG30-MG3Z	Terminated	[12]
NPC-17731	DMGVIZY	Asthma	CA23	Terminated	[13]

27 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(D)Arg-Arg-Pro-Hyp-Gly-Phe-Ser-(d)Phe-Phe-Arg	DMWE42T	Discovery agent	N.A.	Investigative	[14]
(D)Arg-Arg-Pro-Hyp-Gly-Thi-Cys-(D)Phe-Phe-Cys-Arg	DMYSE3O	Discovery agent	N.A.	Investigative	[14]
(D)Arg-Arg-Pro-Hyp-Gly-Thi-Ser-(D)Tic-Aoc-Arg	DMLSJKM	Discovery agent	N.A.	Investigative	[14]
(D)Arg-Arg-Pro-Hyp-Gly-Thi-Ser-(D)Tic-Tic-Arg	DMP0627	Discovery agent	N.A.	Investigative	[14]
bradyzide	DM0DWSR	Discovery agent	N.A.	Investigative	[15]
Breceptin	DM21ZBU	Solid tumour/cancer	2A00-2F9Z	Investigative	[16]
chroman 28	DMVDB7S	Discovery agent	N.A.	Investigative	[17]
FR167344	DM2W5VA	Discovery agent	N.A.	Investigative	[18]
FR190997	DM0G4HP	Discovery agent	N.A.	Investigative	[19]
FR191413	DM75VHN	Discovery agent	N.A.	Investigative	[20]
H-DArg-Arg-Pro-Hyp-Gly-Igl-Ser-D-BT-OH(JMV1638)	DM6839G	Discovery agent	N.A.	Investigative	[6]
H-Lys-Arg-Pro-Hyp-Gly-Igl-Ser-D-BT-OH(JMV1645)	DMDXIS7	Discovery agent	N.A.	Investigative	[6]
H-Lys-Arg-Pro-Hyp-Gly-Thi-Ser-D-BT-OH(JMV1669)	DMTGU0L	Discovery agent	N.A.	Investigative	[6]
JMV1431	DMAR3M2	Discovery agent	N.A.	Investigative	[6]
kallidin	DMRT6OP	Discovery agent	N.A.	Investigative	[21]
LF-160335	DMOEQTN	Discovery agent	N.A.	Investigative	[22]
Met-Lys-bradykinin	DMZBLQD	Discovery agent	N.A.	Investigative	[23]
NPC-349	DMU426Z	Discovery agent	N.A.	Investigative	[21]
PMID12723943C12	DMR1MCD	Discovery agent	N.A.	Investigative	[24]
PMID12812482C11	DMYXDK5	Discovery agent	N.A.	Investigative	[25]
PS020990	DMK6HMS	Discovery agent	N.A.	Investigative	[26]
Quinapril analogue	DM0BEZS	Discovery agent	N.A.	Investigative	[27]
T-kinin	DMYGXHK	Discovery agent	N.A.	Investigative	[28]
WIN 64338	DMTE0YJ	Discovery agent	N.A.	Investigative	[29]
[des-Arg9]bradykinin	DMEL0SZ	Discovery agent	N.A.	Investigative	[30]
[Leu8,des-Arg9]bradykinin	DM3JHRC	Discovery agent	N.A.	Investigative	[31]
[Sar,D-Phe8,des-Arg9]bradykinin	DMUF7DP	Discovery agent	N.A.	Investigative	[28]

References

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