Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTI6V2A)

• DTT Name: Heme oxygenase 1 (HMOX1) DTT Info
• Gene Name: HMOX1

Molecule-Related Drug & Molecule List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Stannsoporfin	DMEG4TC	Neonatal hyperbilirubinemia	KA87	Phase 2	[1]

9 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone	DMOTJWZ	Discovery agent	N.A.	Investigative	[2]
12-Phenylheme	DMLR2FB	Discovery agent	N.A.	Investigative	[3]
2-Phenylheme	DMPIQTE	Discovery agent	N.A.	Investigative	[3]
2-Propanol, Isopropanol	DML5O0H	Discovery agent	N.A.	Investigative	[3]
Biliverdine Ix Alpha	DMCA0WJ	N. A.	N. A.	Investigative	[3]
Formic Acid	DMNFZC6	Discovery agent	N.A.	Investigative	[3]
Heme	DMGC287	Discovery agent	N.A.	Investigative	[2]
Tin protoporphyrin	DMTXJ5S	Discovery agent	N.A.	Investigative	[4]
Verdoheme	DM7NRK5	Discovery agent	N.A.	Investigative	[5]

References

• [1] Chemoprevention of severe neonatal hyperbilirubinemia. Semin Perinatol. 2004 Oct;28(5):365-8.
• [2] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
• [3] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [4] Adenovirus-mediated heme oxygenase-1 gene delivery inhibits injury-induced vascular neointima formation. Circulation. 2001 Nov 27;104(22):2710-5.
• [5] DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.