Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTIA0J5)

• DTT Name: Bacterial 70S ribosomal RNA (Bact 70S rRNA) DTT Info
• Gene Name: Bact 70S rRNA

Molecule-Related Drug & Molecule List

3 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Capreomycin	DMNZBRY	Bacterial infection	1A00-1C4Z	Approved	[1]
Capreomycin Sulfate	DM346QI	Tuberculosis	1B10-1B1Z	Approved	[2]
Viomycin sulfate	DMZYLFC	Bacterial infection	1A00-1C4Z	Approved	[3]

References

• [1] Interaction between the ribosomal subunits: 16S rRNA suppressors of the lethal DeltaA1916 mutation in the 23S rRNA of Escherichia coli. Mol Genet Genomics. 2007 Sep;278(3):307-15.
• [2] The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome.Nat Struct Mol Biol.2010 Mar;17(3):289-93.
• [3] The antibiotic viomycin traps the ribosome in an intermediate state of translocation.Nat Struct Mol Biol.2007 Jun;14(6):493-7.