General Information of DTT (ID: TTLT9XQ)

DTT Name Integrin beta-7 (ITGB7) DTT Info
Gene Name ITGB7

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
1 Approved Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Vedolizmab DMV3YMX Crohn disease DD70 Approved [1]
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3 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rhumab Beta7 DMGOTK4 Ulcerative colitis DD71 Phase 3 [2]
AMG-181 DMODJTX Crohn disease DD70 Phase 2 [3]
PTG-100 DMQNRGE Ulcerative colitis DD71 Phase 1 [4]
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Molecule Interaction Atlas

References

1 Clinical pipeline report, company report or official report of Takeda (2009).
2 A randomised phase I study of etrolizumab (rhuMAb beta7) in moderate to severe ulcerative colitis. Gut. 2013 Aug;62(8):1122-30.
3 Pharmacology of AMG 181, a human anti-alpha4 beta7 antibody that specifically alters trafficking of gut-homing T cells. Br J Pharmacol. 2013 May;169(1):51-68.
4 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)