General Information of DTT (ID: TTLVP78)

DTT Name Dihydroorotate dehydrogenase (DHODH) DTT Info
Gene Name DHODH

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Discontinued Drug(s)
Approved Drug(s)
Clinical Trial Drug(s)
1 Approved Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Teriflunomide DMQ2FKJ Hyperlipidaemia 5C80 Approved [1]
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4 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
BREQUINAR DMKGM42 Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2 [2]
Vidofludimus DM0POWG Inflammatory bowel disease DD72 Phase 2 [3]
BAY2402234 DMRL6W5 Myeloid leukaemia 2B33.1 Phase 1 [4]
LAS-186323 DMV80DP Multiple sclerosis 8A40 Phase 1 [5]
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2 Discontinued Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
FK778 DMH6QAI Kidney/heart transplant rejection NE84 Discontinued in Phase 2 [6]
HR325 DM51GZS Rheumatoid arthritis FA20 Discontinued in Phase 2 [7]
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Molecule Interaction Atlas

References

1 Nat Rev Drug Discov. 2013 Feb;12(2):87-90.
2 DOI: 10.1203/00006450-198807000-00137
3 Company report (4SC)
4 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5 Clinical pipeline report, company report or official report of Aslanpharma.
6 Immunosuppression with FK778 and mycophenolate mofetil in a rat cardiac transplantation model. Transplantation. 2003 Dec 15;76(11):1627-9.
7 In vitro and in Vivo inhibition of immunoglobulin secretion by the immunosuppressive compound HR325 is reversed by exogenous uridine. Scand J Immunol. 2002 Jul;56(1):35-42.