General Information of DTT (ID: TTM8FR7)

DTT Name KRAS messenger RNA (KRAS mRNA) DTT Info
Gene Name KRAS

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Investigative Drug(s)
4 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
ISIS 6957 DMTHO4A Discovery agent N.A. Investigative [1]
ISIS 6958 DM83EK9 Discovery agent N.A. Investigative [2]
ISIS 7453 DMOX7FJ Discovery agent N.A. Investigative [2]
PNT-300 DM8WJQ0 Solid tumour/cancer 2A00-2F9Z Investigative [3]
------------------------------------------------------------------------------------
Molecule Interaction Atlas

References

1 Antisense oligonucleotides demonstrate a dominant role of c-Ki-RAS proteins in regulating the proliferation of diploid human fibroblasts. J Biol Chem. 1996 Nov 8;271(45):28259-65.
2 US patent application no. 5,965,722, Antisense inhibition of ras gene with chimeric and alternating oligonucleotides.
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2824).