Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTOA18V)

DTT Name	Rab proteins geranylgeranyltransferase component A 1 (CHM) DTT Info
Gene Name	CHM

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

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3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BIIB111	DMQCE1T	Choroideremia	9B61	Phase 3	[1]
SPK-7001	DMEVGI9	Choroidal dystrophy	9B61	Phase 1/2	[2]
4D-110	DMUXAM8	Choroideremia	9B61	Phase 1	[3]
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Molecule Interaction Atlas

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References

1	ClinicalTrials.gov (NCT03496012) A Randomised, Open Label, Outcomes-Assessor Masked, Prospective, Parallel Controlled Group, Phase 3 Clinical Trial of Retinal Gene Therapy for Choroideremia Using an Adeno-Associated Viral Vector (AAV2) Encoding Rab Escort Protein 1 (REP1). U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Spark Therapeutics.
3	Clinical pipeline report, company report or official report of 4D Molecular Therapeutics