General Information of DTT (ID: TTOISYB)

DTT Name Proto-oncogene Mas (MAS) DTT Info
Gene Name MAS1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
2 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Angiotensin-(1-7) DM76GZ0 Sarcoma 2A60-2C35 Phase 3 [1]
DSC-127 DMM0HAE Diabetic foot ulcer BD54 Phase 3 [1]
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3 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
AR234960 DMTN10D Discovery agent N.A. Investigative [2]
AR244555 DM68QY0 Discovery agent N.A. Investigative [2]
AVE 0991 DM9R3WT Discovery agent N.A. Investigative [3]
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Molecule Interaction Atlas

References

1 New therapeutic pathways in the RAS. J Renin Angiotensin Aldosterone Syst. 2012 Dec;13(4):505-8.
2 Inhibition of Mas G-protein signaling improves coronary blood flow, reduces myocardial infarct size, and provides long-term cardioprotection. Am J Physiol Heart Circ Physiol. 2012 Jan 1;302(1):H299-311.
3 Nonpeptide AVE 0991 is an angiotensin-(1-7) receptor Mas agonist in the mouse kidney. Hypertension. 2004 Oct;44(4):490-6.