Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTP9K3Q)

• DTT Name: SOD1 messenger RNA (SOD1 mRNA) DTT Info
• Gene Name: SOD1

Molecule-Related Drug & Molecule List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tofersen	DM0AEDT	Amyotrophic lateral sclerosis	8B60.0	Approved	[1]

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS-SOD1	DMV1BTP	Amyotrophic lateral sclerosis	8B60.0	Phase 1	[2]

7 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS 150450	DMMBW13	Discovery agent	N.A.	Investigative	[3]
ISIS 150451	DM1DCFP	Discovery agent	N.A.	Investigative	[3]
ISIS 150452	DMQE7BH	Discovery agent	N.A.	Investigative	[3]
ISIS 150453	DMKCG41	Discovery agent	N.A.	Investigative	[3]
ISIS 150454	DMW0Y75	Discovery agent	N.A.	Investigative	[3]
ISIS 150463	DMFUM62	Discovery agent	N.A.	Investigative	[3]
ISIS 150464	DM1IC54	Discovery agent	N.A.	Investigative	[3]

References

• [1] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [2] Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).
• [3] US patent application no. 7,132,530, Antisense modulation of superoxide dismutase 1, soluble expression.