General Information of DTT (ID: TTPNE41)

DTT Name CI Man-6-P receptor (IGF2R) DTT Info
Gene Name IGF2R

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Clinical Trial Drug(s)
Preclinical Drug(s)
2 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Juvidex DMZKYNO Sarcoidosis 4B20.5 Phase 2 [1]
PXS-25 DMVQJOS Fibrosis GA14-GC01 Phase 1 [2]
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1 Preclinical Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
EP-128504 DMJEKQM Solid tumour/cancer 2A00-2F9Z Preclinical [3]
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Molecule Interaction Atlas

References

1 Hypertrophic Scarring and Keloids: Pathomechanisms and Current and Emerging Treatment Strategies. Mol Med. 2011 Jan-Feb; 17(1-2): 113-125.
2 Cation-independent mannose 6-phosphate receptor inhibitor (PXS25) inhibits fibrosis in human proximal tubular cells by inhibiting conversion of latent to active TGF-beta1. Am J Physiol Renal Physiol.2011 Jul;301(1):F84-93.
3 The discovery and mechanism of action of novel tumor-selective and apoptosis-inducing 3,5-diaryl-1,2,4-oxadiazole series using a chemical genetics approach. Mol Cancer Ther. 2005 May;4(5):761-71.