Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTQKWA4)

• DTT Name: Fungal Cell membrane ergosterol (Fung CME) DTT Info
• Gene Name: Fung CME

Molecule-Related Drug & Molecule List

3 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Amphotericin B	DMTAJQE	Acne vulgaris	ED80	Approved	[1]
Candicidin	DMNZSC1	Bacterial infection	1A00-1C4Z	Approved	[2]
Nystatin	DM63QS9	Cutaneous candidiasis	1F23.14	Approved	[3]

References

• [1] Comparative molecular dynamics simulations of amphotericin B-cholesterol/ergosterol membrane channels. Biochim Biophys Acta. 2002 Dec 23;1567(1-2):63-78.
• [2] Mode of Action of the Polyene Antibiotic Candicidin: Binding Factors in the Wall of Candida albicans
• [3] Cholesterol and Ergosterol Influence Nystatin Surface Aggregation: Relation to Pore Formation